EurekAlert! InContext Modules

Public Release: 27-Oct-2011

Science
Physicists manipulate single molecules to unravel secrets of protein folding
Munich-based physicists are opening a new window on protein folding, using a technique that lets them grab the ends of a single protein molecule and pull, making continuous, direct measurements as it unfolds and refolds. Their latest study of the protein calmodulin reveals a complex network of intermediate states along the way to functionally correct folded forms. Better understanding of protein folding is essential because incorrectly folded proteins cause diseases such as Alzheimer's and Parkinson's.

Deutsche Forschungsgemeinschaft, Technische Universitaet Muenchen, Elite Network of Bavaria

Public Release: 24-Oct-2011

AMIA's 35th Annual Symposium on Biomedical and Health Informatics
21 Fellows inducted into American College of Medical Informatics
Twenty-one new Fellows were elected in the American College of Medical Informatics, an honorary college for those you have made significant and sustained contributions to a rapidly growing field, strategically tied to implementation of health information technology and EHRs.

Public Release: 20-Oct-2011

AMIA 2011 Annual Symposium
AMIA honors informatics professionals who are improving health, changing the world
AMIA, the association for informatics professionals, highlights four individuals who have made extraordinary contributions to health care through the application of informatics.

American Medical Informatics Association

Public Release: 20-Oct-2011

PLOS Computational Biology
Failing to bridge the gap between test tubes, animals, and human biology
Reasoning used in many highly cited cancer publications to support the relevance of animal and test tube experiments to human cancer is questionable, according to a study by researchers from Universite Libre de Bruxelles published in the open-access journal PLoS Computational Biology on Oct. 20, 2011.

Public Release: 19-Oct-2011
BUSM receives $13.6m grant to develop tools for the early detection of lung cancer
Boston University School of Medicine (BUSM) is the lead institution on a $13.6 million study aimed at developing novel technologies for the early detection of lung cancer.

US Department of Defense

Public Release: 19-Oct-2011

AMIA's 35th Annual Symposium on Biomedical and Health Informatics
AMIA honors Regenstrief Institute's President and CEO with 2011 Morris F. Collen Award
The Morris F. Collen Award goes to an individual each year who has exemplified personal commitment and dedication to advancing informatics in health and biomedicine. Pioneer Morris Collen was the first to bring EHRs to Kaiser Permanente and champion the cause of computer-assisted health-care delivery.

American Medical Informatics Association

Public Release: 19-Oct-2011

Genome Biology
The cannabis genome: How hemp got high
Throughout history, Cannabis sativa has been exploited by humanity. Hemp seed oil is rich in omega 6, and its fiber is used in the production of fabrics. Marijuana is known for its mind-altering properties. The changes to the genome that led to drug-producing plants is a mystery of cannabis evolution, but one that has now been solved, thanks to an article published today in BioMed Central's open-access journal Genome Biology.

Public Release: 19-Oct-2011

Anesthesiology 2011
3 factors could point to your fate after surgery
Duke University Medical Center researchers have verified data that suggest three medical factors appear to correlate with mortality for a patient who has been under anesthesia for an operation.

Public Release: 18-Oct-2011
Scripps launches whole genome sequencing study to find root causes of idiopathic diseases
Scripps Health announced today it has launched an innovative clinical research study that is using whole genome sequencing to help determine the causes of idiopathic human diseases - those serious, rare and perplexing health conditions that defy a diagnosis or are unresponsive to standard treatments. To date, only a select few institutions across America are using whole genome sequencing for purposes such as diagnosing patients, predicting disease risk and understanding health.

Anne and Henry Zarrow Foundation

Public Release: 17-Oct-2011
Genomatix to partner in $41 million European epigenomics consortium
Genomatix is among the 41 partners of the BLUEPRINT epigenome consortium funded by the European Commission as a high-impact project within its seventh framework program. Genomatix' contributions will be next generation sequencing data analysis and the development of an intuitive GUI to make the project's results easily accessible to researchers within and outside the consortium.

European Commission

Public Release: 17-Oct-2011

Nature Biotechnology
Genomic sequence and comparison of 2 macaques reveal new insights into biomedical research
The South China Center for Innovative Pharmaceuticals, Sun Yat-Sen University, and BGI, the world's largest genomic organization, announced that they were among the research organizations from China, the US and the UK comprising an international research group that completed the genome sequence and comparison of two non-human primate animal models -- the Chinese rhesus macaque and the cynomolgus.

Public Release: 17-Oct-2011

Genome Research
Independent research teams identify first infectious agent associated with colon cancer
For the first time, a specific microorganism has been found to be associated with human colorectal cancer. In two studies published online today in Genome Research, independent research teams have identified Fusobacterium in colon cancer tissue, a finding that could open new avenues for diagnosis and treatment of the disease.

Public Release: 13-Oct-2011

PLOS Computational Biology
Differing structures underlie differing brain rhythms in healthy and ill
Virtual brains modeling epilepsy and schizophrenia display less complexity among functional connections, and other differences compared to healthy brain models, researchers at Case Western Reserve University School of Medicine report. The researchers worked backward from brain rhythms – the oscillating patterns of electrical activity in the brain recorded on electroencephalograms - from both healthy and ill individuals.

Mt. Sinai Foundation, Alfred P. Sloan Foundation, Choose Ohio First grant

Public Release: 13-Oct-2011

PLOS Computational Biology
Twitter data used to track vaccination rates and attitudes
The first case study in how social-media sites can affect the spread of a disease has been designed and implemented by a scientist at Penn State University studying attitudes toward the H1N1 vaccine. The method is expected to be repeated in the study of other diseases.

Society in Science-Branco Weiss Fellowship

Public Release: 13-Oct-2011
Scientists in Singapore and Europe to collaborate
Scientists in Singapore and Europe will have new avenues for scientific interaction, following a cooperation agreement between EMBO, EMBC and the government of Singapore.

Public Release: 13-Oct-2011

PLOS Computational Biology
Agricultural pest management program efficiency challenged by information diffusion barriers among farmers
While international pest management programs have long relied on farmer cooperation to spread pest control information at larger scales, a study by French researchers published in the open-access journal PLoS Computational Biology on Thursday, Oct. 13, 2011, reveals that slow information diffusion within farmer communities gives rise to significant lags in implementation of pest management procedures.

Public Release: 12-Oct-2011

Nature
Genome sequencing unlocks the mysteries of naked mole rat
Genome sequencing by international research team unlocks the mysteries of naked mole rat.

Public Release: 11-Oct-2011

Science
ISU plant pathologist updates science community on groundbreaking research
In the two years since the journal Science published an article by ISU's Adam Bogdanove about his groundbreaking gene research, scientists around the world have built on his findings to explore further breakthroughs. Now Bogdanove updates the scientific community on where the research has been since 2009 and where it is heading.

Public Release: 11-Oct-2011
BGI develops first monkey exome sequencing platform for biomedical research
BGI develops first monkey exome sequencing platform for biomedical research.

Public Release: 6-Oct-2011

PLOS Computational Biology
Incompatible assumptions common in biomedical research
Strong, incompatible views are common in biomedicine but are largely invisible to biomedical experts themselves, creating artificial barriers to effective modeling of complex biological phenomena. Researchers at the University of Chicago explored the diversity in views among scientists researching the process of cancer metastasis and found ubiquitous disagreement around assumptions in any model of the progression of cancer cells from their original location to other parts of the body.

Public Release: 2-Oct-2011

Nature Biotechnology
Advancing next gen biofuels by turning up the heat on biomass pretreatment processes
Many enzymes currently used in biofuel production are derived from species that thrive at room temperature to nearly body temperature. The conversion process at these temperatures takes time, during which contaminants can reduce the final yield. Published online Oct. 2 in Nature Biotechnology, an international team of scientists compared the finished genomes of fungi that thrive in high-temperature environments above 45°C and whose cellulases would therefore be useful for accelerating the biofuel production process.

US Department of Energy

Public Release: 28-Sep-2011

Journal of the American Animal Hospital Association
University of Missouri study finds risk factors for cat cancer, could have human implications
A recent, large-scale study on cat intestinal cancer has provided new insight into a common pet disease and its causes; the findings could ultimately benefit humans.

Public Release: 28-Sep-2011
OGI and MaRS Innovation invest in peptide therapeutics
Through its Pre-Commercialization Business Development Fund (PBDF), the Ontario Genomics Institute (OGI) has invested $100,000 into research that is aimed at novel methodologies to create effective peptide and protein based drugs.

Ontario Genomics Institute, MaRS Innovation

Public Release: 28-Sep-2011
TGen Drug Development recognized for economic development of Arizona biosciences
TGen Drug Development won a Fast Lane award from the Arizona BioIndustry Association for promoting the economic development of Arizona biosciences. TD2, a subsidiary of the Translational Genomics Research Institute, provides world-class clinical and regulatory expertise to biopharmaceutical companies using cutting-edge technology to minimize the risks in cancer drug development. TD2 works to shorten the development cycles for anti-cancer agents and improve their success rates.

Public Release: 28-Sep-2011

Science Translational Medicine
Saving heart attack victims with computer science
Newly discovered subtle markers of heart damage hidden in plain sight among hours of EKG recordings could help doctors identify which heart attack patients are at high risk of dying soon.

National Science Foundation, Center for Integration of Medicine and Innovative Technology, Quanta Computer, Harvard-MIT Division of Health Sciences and Technology


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