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Key: Meeting M      Journal J      Funder F

Showing releases 676-700 out of 714.

<< < 23 | 24 | 25 | 26 | 27 | 28 | 29 > >>

Public Release: 5-Sep-2012
Huge human gene study includes Penn State University research
The first integrated understanding of how the human genome functions will be published this week -- the triumphant result of a collaborative five-year project called ENCODE, involving more than 440 researchers working in 32 labs worldwide. Penn State's contribution involves using the new ENCODE data to help explain how genetic variants that do not affect the structure of encoded proteins could affect a person's susceptibility to disease.
NIH/National Human Genome Research Institute, National Science Foundation

Contact: Barbara K. Kennedy
Penn State

Public Release: 5-Sep-2012
Fast forward for biomedical research: ENCODE scraps the junk
An international team of researchers has revealed that much of what has been called 'junk DNA' in the human genome is actually a massive control panel with millions of switches regulating the activity of our genes. Discovered by hundreds of scientists working on the ENCODE Project, the new information is so comprehensive and complex that it has given rise to a new publishing model.
NIH/National Human Genome Research Institute

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 5-Sep-2012
Genome Research
The ENCODE Project publishes new genomic insights in special issue of Genome Research
Genome Research publishes online and in print today a special issue dedicated to The ENCODE (ENCyclopedia Of DNA Elements) Project, whose goal is to characterize all functional elements in the human genome. The entire issue will be freely available online on Sept. 6 to coordinate with additional ENCODE Consortium publications in Nature, Genome Biology, and other journals.

Contact: Peggy Calicchia
Cold Spring Harbor Laboratory

Public Release: 4-Sep-2012
Arteriosclerosis, Thrombosis and Vascular Biology
Vitamin D supplements do not improve cholesterol as previous research suggested
A team of scientists from Rockefeller University has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D.
National Institutes of Health

Contact: Joseph Bonner
Rockefeller University

Public Release: 4-Sep-2012
Eurofins MWG Operon reinforces NGS capability with Illumina HiSeq 2500 and Illumina MiSeq
Eurofins MWG Operon, one of the pioneers and key providers of next generation sequencing (NGS), has added an Illumina HiSeq 2500 and an Illumina MiSeq sequencer to its fleet of NGS sequencers.

Contact: Dr. Georg Gradl
Eurofins Genomics

Public Release: 4-Sep-2012
Study points to new target for cancers resistant to Iressa and Herceptin
A more-sensitive method to analyze protein interactions has uncovered a new way that cancer cells may use the cell-surface molecule HER3 to drive tumor progression following treatment with HER1 and HER2 inhibitors. This study shows that HER3 could be up to 10 times more effective than HER2, the target for Herceptin, in recruiting the proteins that drive the rapid proliferation, enhanced survival and distant spread of cancer.
National Institutes of Health, Cancer Research Foundation, Illinois Department of Public Health

Contact: John Easton
University of Chicago Medical Center

Public Release: 3-Sep-2012
EMBO Journal
Anchoring proteins influence glucose metabolism and insulin release
Scientists from the United States and Sweden have discovered a new control point that could be important as a drug target for the treatment of diabetes and other metabolic diseases.

Contact: Barry Whyte
European Molecular Biology Organization

Public Release: 3-Sep-2012
Proceedings of the National Academy of Sciences
Mass spec makes the clinical grade
A new mass spectrometry-based test identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online. The head-to-head comparison using blood samples from cancer patients measured biomarkers, proteins whose presence identifies a disease or condition. The technique should be able to speed up development of protein-specific diagnostic tests and treatment.
National Institutes of Health, Department of Energy

Contact: Mary Beckman
DOE/Pacific Northwest National Laboratory

Public Release: 31-Aug-2012
Genome Medicine
BUSM researchers find potential key to halt progression, reverse damage from emphysema
A study led by researchers at Boston University School of Medicine has shown that a compound used in some skin creams may halt the progression of emphysema and reverse some of the damage caused by the disease. When the compound Gly-His-Lys was applied to lung cells from patients with emphysema, normal gene activity in altered cells was restored and damaged aspects of cellular function were repaired.
NIH/National Heart, Lung, and Blood Institute

Contact: Jenny Eriksen
Boston University Medical Center

Public Release: 30-Aug-2012
PLOS Computational Biology
Rice, MD Anderson scientists probe mystery of operon evolution
New research this week in PLOS Computational Biology suggests a possible explanation for the organization of operons, jointly controlled clusters of genes that evolved in bacterial chromosomes. Operons, which are found in the chromosomes of bacteria but not in more advanced organisms, have puzzled biologists since their discovery in the 1960s. The new study suggests operons evolved as a means of reducing "noise" in biochemical signal processing.
National Library of Medicine, National Institute of General Medical Sciences

Contact: Jade Boyd
Rice University

Public Release: 30-Aug-2012
Proceedings of the National Academy of Sciences
Keep your distance! Why cells and organelles don't get stuck
Biomembranes enclose biological cells and surround organelles that carry out vital functions. Scientists have long known in principle how biomembranes are built up, and also that water molecules play a role in maintaining optimal spacing between neighboring membranes. Now, with the help of computer simulations, scientists of the Technische Universität München and the Freie Universitaet Berlin have discovered two different mechanisms that prevent neighboring membrane surfaces from sticking together. Their results appear in PNAS.
German Research Foundation, Ministry for Economy & Technology/AiF framework

Contact: Patrick Regan
Technische Universitaet Muenchen

Public Release: 30-Aug-2012
Science study shows 'promiscuous' enzymes still prevalent in metabolism
Open an undergraduate biochemistry textbook and you will learn that enzymes are highly efficient and specific in catalyzing chemical reactions in living organisms, and that they evolved to this state from their "sloppy" and "promiscuous" ancestors to allow cells to grow more efficiently. This fundamental paradigm is being challenged in a new study by bioengineers at the University of California, San Diego.
National Institutes of Health, US Department of Energy

Contact: Catherine Hockmuth
University of California - San Diego

Public Release: 30-Aug-2012
Ant behavior tracked by tiny radio receivers in pioneering scientific study
Researchers from the University of York are fitting one thousand northern hairy wood ants with tiny radio receivers in a world first experiment to find out how they communicate and travel between their complex nests.

Contact: David Garner
University of York

Public Release: 29-Aug-2012
Computer viruses could take a lesson from showy peacocks
Computer viruses are constantly replicating throughout computer networks and wreaking havoc. But what if they had to find mates in order to reproduce? In the current issue of Evolution, Michigan State University researchers created the digital equivalent of spring break to see how mate attraction played out through computer programs, said Chris Chandler, MSU postdoctoral researcher at MSU's BEACON Center for the Study of Evolution in Action.
National Science Foundation

Contact: Layne Cameron
Michigan State University

Public Release: 28-Aug-2012
Journal of Thoracic Oncology
Not all lung cancer patients who could benefit from crizotinib are identified by FDA-approved test
A recent University of Colorado Cancer Center case study published in the Journal of Thoracic Oncology describes the never-before-seen case of a patient who tested negative for EML4-ALK fusion based on the well-defined criteria for FISH assay as approved by FDA, but nevertheless experienced remission after treatment with crizotinib.

Contact: Garth Sundem
University of Colorado Denver

Public Release: 28-Aug-2012
Nature Genetics
Chinese scientists successfully crack the genome of diploid cotton
The international research team led by Chinese Academy of Agricultural Sciences and BGI have completed the genome sequence and analysis of a diploid cotton -- Gossypium raimondii.

Contact: Jia Liu
BGI Shenzhen

Public Release: 24-Aug-2012
Lessons from Bangladesh
Before he left for Bangladesh to conduct a workshop this summer, UC Riverside's Glenn Hicks did not quite know what to expect. What he knew was that he would be leading a workshop, called on genomics and proteomics at the University of Dhaka. What his brief visit taught him, though, was that education is critical for all of our futures and that with patience education could help overcome even great cultural and economic differences.
World Bank

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 22-Aug-2012
ICAAC 2012
The American Society for Microbiology honors William Hanage
William P. Hanage, Ph.D., Department of Epidemiology, Harvard School of Public Health, has received a 2012 ICAAC Young Investigator Award. Hanage is honored for his work studying the epidemiology and evolution of infectious disease.

Contact: Garth Hogan
American Society for Microbiology

Public Release: 22-Aug-2012
Science Translational Medicine
NIH uses genome sequencing to help quell bacterial outbreak in Clinical Center
A New York City patient carrying a multi-drug-resistant strain of Klebsiella pneumoniae, a microbe frequently associated with hospital-borne infections, introduced the dangerous bacteria into the 243-bed research hospital while participating in a clinical study in the summer of 2011. To get the outbreak under control, Clinical Center staff collaborated with investigators at the National Human Genome Research Institute, also part of NIH, to use genome sequencing in the middle of this active hospital epidemic to learn how the microbe spread.
NIH/National Human Genome Research Institute, Clinical Center

Contact: Raymond MacDougall
NIH/National Human Genome Research Institute

Public Release: 22-Aug-2012
Genome Research
Archived Guthrie cards find a new purpose
Spotting of newborn's blood onto filter paper for disease screening, called Guthrie cards, has become so routine that since 2000, more than 90 percent of newborns in the United States have had Guthrie cards created. In a study published online in Genome Research, researchers have shown that epigenetic information stored on archived Guthrie cards provides a retrospective view of the epigenome at birth, a powerful new application for the card that could help understand disease.

Contact: Peggy Calicchia
Cold Spring Harbor Laboratory

Public Release: 21-Aug-2012
Current Biology
The first ant methylomes uncover the relationship between DNA methylation and caste differentiation
The first ant methylomes uncover the relationship between DNA methylation and caste differentiation.

Contact: Jia Liu
BGI Shenzhen

Public Release: 20-Aug-2012
International Journal of Computational Biology and Drug Design
Anthrax targets
A trawl of the genome of the deadly bacterium Bacillus anthracis has revealed a clutch of targets for new drugs to combat an epidemic of anthrax or a biological weapons attack. The targets are all proteins that are found in the bacteria but not in humans and are involved in diverse bacterial processes such as metabolism, cell wall synthesis and bacterial persistence. The discovery of a range of targets might bode well for creating a drug cocktail that could preclude the emergence of drug resistance.

Contact: Ravi Gutlapalli
Inderscience Publishers

Public Release: 17-Aug-2012
Writing the book in DNA
Using next-generation sequencing technology and a novel strategy to encode 1,000 times the largest data size previously achieved in DNA, a Harvard geneticist encodes his book in life's language.
Office of Naval Research, Agilent Technologies, Wyss Institute

Contact: David Cameron
Harvard Medical School

Public Release: 17-Aug-2012
Iconic Darwin finch genome sequenced in Genome 10K international collaboration
Scientists have sequenced the genome of one of the iconic Galapagos finches first described by Charles Darwin.

Contact: Jia Liu
BGI Shenzhen

Public Release: 16-Aug-2012
Mouse study finds clear linkages between inflammation, bacterial communities and cancer
In a study with inflammation-prone mice, researchers have found a mechanism for the development of colorectal cancer wherein inflammation fosters a change in the gut microbiome including reduced bacterial diversity but also the increased presence of E. coli and related pathogens. Further mouse studies show genes carried by an E. coli variant can cause cancer development. The suspect bacterial genes are found in a high percentage of human colorectal cancer patients.

Contact: James Hathaway
University of North Carolina at Charlotte

Showing releases 676-700 out of 714.

<< < 23 | 24 | 25 | 26 | 27 | 28 | 29 > >>