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Key: Meeting M      Journal J      Funder F

Showing releases 726-750 out of 840.

<< < 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 > >>

Public Release: 30-Mar-2014
Nature Genetics
Genetic mutations warn of skin cancer risk
In a study published in Nature Genetics, researchers have discovered that mutations in a specific gene are responsible for a hereditary form of skin cancer. These mutations inactivate the POT1 gene that protects our chromosomes, and, in turn, results in skin cancer. The mechanism that underlies this form of skin cancer is also a potential target for drug development in this subset of melanoma patients.

Contact: Aileen Sheehy
Wellcome Trust Sanger Institute

Public Release: 27-Mar-2014
TGen and Scottsdale Healthcare cancer expert Dr. Von Hoff receives Hope Funds award
Dr. Daniel D. Von Hoff, who has been instrumental in developing numerous new cancer treatments, is among this year's recipients of the Award of Excellence from the Hope Funds for Cancer Research. Dr. Von Hoff, M.D., FACP, who is Physician-In-Chief and Distinguished Professor at the Translational Genomics Research Institute, and Chief Scientific Officer for Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials, will receive the 2014 Hope Funds Award of Excellence in Medicine.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 27-Mar-2014
Proceedings of the National Academy of Sciences
Cancer researchers find key protein link
A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases.
National Institutes of Health, Cancer Prevention Research Institute of Texas, Israeli Science Foundation, European Research Council

Contact: David Ruth
Rice University

Public Release: 27-Mar-2014
Systematic Biology
Strictly yeast
Researchers at the National Collection of Yeast Cultures at the Institute of Food Research have turned a problem in evolutionary biology into a new tool to better understand phylogeny in closely related species. Resequencing ribosomal DNA in closely related yeast species has given them new information about the origins of modern yeast strains and a useful tool for evolutionary biologists.
Biotechnology and Biological Sciences Research Council

Contact: Andrew Chapple
Norwich BioScience Institutes

Public Release: 27-Mar-2014
National Cancer Institute awards $2.2 million grant to Jackson Professor Yijun Ruan
The National Cancer Institute has awarded a three-year grant totaling $2,168,535 to Professor Yijun Ruan, Ph.D., of The Jackson Laboratory for Genomic Medicine, for his research into the role of non-coding RNAs in cancer and other diseases.
NIH/National Cancer Institute

Contact: Joyce Peterson
Jackson Laboratory

Public Release: 27-Mar-2014
Biodiversity Data Journal
Despatch from the field
A new spider species was discovered during a student field course in Malaysian Borneo. The species was described and submitted online to Biodiversity Data Journal through a satellite internet connection. The manuscript was peer-reviewed and published within two weeks. On the day of publication, software tools extracted the occurrence data of the species and submitted these to the Global Biodiversity Information Facility. In a similar way data was exported to Encyclopedia of Life.

Contact: Tim Hirsch
Pensoft Publishers

Public Release: 26-Mar-2014
How size splits cells
Contrary to previous findings suggesting a protein measures cell length, a different protein is found to measure the cell's surface area.
Biotechnology and Biological Sciences Research Council, National Institutes of Health

Contact: Zoe Dunford
Norwich BioScience Institutes

Public Release: 26-Mar-2014
New database features 710,000 natural history records from Canadian Museum of Nature
A new, free open-access database has opened the collections of Canada's national natural history museum, with 710,000 specimen records available at These cover about 22 percent of the museum's overall collection of plants, animals, fossils and minerals, which have been collected over more than 150 years.

Contact: Dan Smythe
Canadian Museum of Nature

Public Release: 26-Mar-2014
Where do you start when developing a new medicine?
A pioneering public-private research initiative between GSK, the European Bioinformatics Institute and the Wellcome Trust Sanger Institute is to harness the power of 'big data' and genome sequencing to improve the success rate for discovering new medicines. The new Centre for Therapeutic Target Validation aims to address a wide range of human diseases and will share its data openly in the interests of accelerating drug discovery.

Contact: EMBL Press Office
European Molecular Biology Laboratory

Public Release: 26-Mar-2014
Reproducible research, dynamic documents, and push-button publishing
GigaScience, a BGI and BioMed Central journal, announces a major step forward for reproducible research and public data-sharing in the neurosciences with the publication of a huge cache of electrophysiology data important for retinal activity analyses. Very little of this data is publically available: this study provides 366 recordings from 12 electrophysiology studies collected between 1993-2014. The authors standardized these data, made them interoperable, and encapsulated both data and software in a shareable, reproducible format.
Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council, and Wellcome Trust

Contact: Scott Edmunds

Public Release: 26-Mar-2014
Natural history must reclaim its place
A group of scientists argues in the April BioScience that the study of natural history has waned in recent decades in developed countries. Declining course requirements and support for herbaria are among the documented evidence. Yet costly mistakes in policy relating to natural resources, agriculture, and health might have been avoided by paying attention to organisms' natural history, and future policies will be improved if natural history knowledge is used and expanded. New technologies offer ways to increase natural history research partnerships.
National Science Foundation, University of Washington, Prescott College, Walker Chair in Natural History, National Center for Ecological Analysis and Synthesis

Contact: Jennifer Williams
703-674-2500 x209
American Institute of Biological Sciences

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
For neurons in the brain, identity can be used to predict location
There are many types of neurons of neurons, defined largely by the patterns of genes they use, and they 'live' in distinct brain regions. But researchers do not yet have a comprehensive understanding of these neuronal types and how they are distributed in the brain. A team of scientists at Cold Spring Harbor Laboratory describes a new mathematical model that combines large data sets to predict where different types of cells are located within the brain.
NIH/National Institute on Drug Abuse

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 23-Mar-2014
Nature Methods
'MaMTH' advance: New technology sheds light on protein interactions
Scientists have a better way to study human proteins -- large molecules that are part of every cell in the body -- thanks to a new technology developed by University of Toronto researchers. The technology tracks a class of proteins called membrane proteins as they interact with other proteins to either maintain health or contribute to disease.
Ontario Genomics Institute, Canadian Institutes of Health Research, Canadian Cancer Society

Contact: Jim Oldfield
University of Toronto

Public Release: 23-Mar-2014
Nature Genetics
TGen-led study discovers genetic cause of rare type of ovarian cancer
The cause of a rare type of ovarian cancer that most often strikes girls and young women has been uncovered by an international research team led by the Translational Genomics Research Institute, according to a study published online today by the renowned scientific journal, Nature Genetics. The findings revealed a 'genetic superhighway' mutation in a gene found in the overwhelming majority of patients with small cell carcinoma of the ovary, hypercalcemic type, or SCCOHT.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 21-Mar-2014
With a few finger taps, draw genetic pedigrees at point of care with new app
Long used in genetic medicine, pedigrees are diagrams that show how inherited diseases may recur in a particular family. A new app adds a digital spin, letting clinicians create pedigrees with a few finger taps during a patient encounter.
NIH/National Human Genome Research Institute

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 20-Mar-2014
Cancer Cell
Study reveals a major mechanism driving kidney cancer progression
The shortage of oxygen, or hypoxia, created when rapidly multiplying kidney cancer cells outgrow their local blood supply can accelerate tumor growth by causing a nuclear protein called SPOP -- which normally suppresses tumor growth -- to move out of the nucleus to the cytoplasm, where it has the opposite effect, promoting rapid proliferation. This cytoplasmic accumulation of SPOP is sufficient to convey tumorigenic properties onto otherwise non-tumorigenic cells.
National Institutes of Health, Beijing Science Foundation, Keck Foundation, Chicago Community Trust, Chicago Biomedical Consortium

Contact: John Easton
University of Chicago Medical Center

Public Release: 19-Mar-2014
World Journal of Surgery
TGen study identifies gene fusion as likely cause of rare type of thyroid cancer
In a scientific first, the fusion of two genes, ALK and EML4, has been identified as the genetic driver in an aggressive type of thyroid cancer, according to a study by the Translational Genomics Research Institute. These groundbreaking findings are based on genetic sequencing of tumor cells from a 62-year-old patient with an aggressive tall cell variant of papillary thyroid cancer, according to the study published Tuesday, March 18, in the World Journal of Surgery.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 19-Mar-2014
Molecular Systems Biology
101 liver cancer drug candidates pave the way to personalized medicine
The heart disease drug perhexiline is one of 101 compounds predicted to prevent cancer growth in most patients suffering from our most common liver cancer, HCC. This is an outcome from a novel simulation-based approach using personal sets of proteins of six HCC patients. 'This is the first time personalized models have been used to find and evaluate new potential drugs,' says professor Jens Nielsen at Chalmers University of Technology.
Knut and Alice Wallenberg Foundation

Contact: Christian Borg
Chalmers University of Technology

Public Release: 18-Mar-2014
Journal of Economic Entomology
Planting cotton early may mean less stink bug damage
New research published in the Journal of Economic Entomology shows that planting cotton early in the planting window will allow growers to escape peak stink bug pressure and thereby possibly eliminate or minimally reduce the number of sprays required to manage them.

Contact: Richard Levine
Entomological Society of America

Public Release: 18-Mar-2014
From DNA to diagnosis
Compared to 10 years ago, sequencing the human genome has plummeted in cost by one-million-fold and can be completed in a fraction of the time. Yet there are still barriers preventing DNA sequence information from routinely being incorporated into patient care. The USTAR Center for Genetic Discovery is partnering with California-based Omicia Inc. to make patient genome analysis as routine as a blood test.

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 18-Mar-2014
TGen-led study spotlights dog DNA role in developing new therapies for human cancers
Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof-of-concept study led by the National Cancer Institute and the Translational Genomics Research Institute.
National Institutes of Health

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 17-Mar-2014
Nature Methods
Immunologists present improved mass spectrometric method for proteomic analyses
Mass spectrometry is a highly sensitive method of measurement that has been used for many years for the analysis of chemical and biological materials. Scientists at the Institute of Immunology of the University Medical Center of Johannes Gutenberg University Mainz have now significantly improved this analytical method that is widely employed within their field.

Contact: Dr. Stefan Tenzer
Johannes Gutenberg Universitaet Mainz

Public Release: 17-Mar-2014
Closer to detecting preeclampsia
Researchers have found a set of biomarkers in urine and serum samples that were different between women with preeclampsia, women with normal pregnancies and women who were not pregnant. These biomarkers tell the story of what is happening to the metabolism of women who have developed preeclampsia.

Contact: Marie Austdal
Norwegian University of Science and Technology

Public Release: 16-Mar-2014
Nature Genetics
Novel gene-finding approach yields a new gene linked to key heart attack risk factor
Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders. But even more significant is how they found the gene, which had been hiding in plain sight in previous hunts for genes that influence cardiovascular risk.
National Institutes of Health, Norwegian HUNT

Contact: Kara Gavin
University of Michigan Health System

Public Release: 16-Mar-2014
Newly identified small-RNA pathway defends genome against the enemy within
For a plant to create reproductive cells, it must first erase a series of tags attached to DNA across the genome that distinguish active and inactive genes. But the marks also keep a host of damaging 'jumping genes' inactive. As the cell wipes away the marks, it activates transposons, which can cause genetic damage. Researchers at CSHL have discovered a fail-safe mechanism that helps to keep transposons inactive even when these marks are erased.
DuPont Pioneer, National Institutes of Health, Howard Hughes Medical Institute

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Showing releases 726-750 out of 840.

<< < 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 > >>