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Key: Meeting
Showing releases 76-100 out of 344. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>
Public Release: 18-Sep-2012
BGI Tech develops whole exome sequencing analysis of FFPE DNA samples to boost biomedicine BGI Tech Solutions Co., Ltd., a subsidiary company of BGI, announced today that they have achieved whole exome sequencing analysis of total degraded DNA as low as 200 ng from formalin fixed paraffin embedded samples. Contact: Jia Liu Public Release: 17-Sep-2012
New research presents most extensive pictures ever of an organism's DNA mutation processes Biologists and informaticists at Indiana University have produced one of the most extensive pictures ever of mutation processes in the DNA sequence of an organism, elucidating important new evolutionary information about the molecular nature of mutations and how fast those heritable changes occur. Contact: Steve Chaplin Public Release: 17-Sep-2012
Blue Brain Project accurately predicts connections between neurons In a landmark paper, published the week of Sept. 17 in PNAS, the EPFL's Blue Brain Project has identified key principles that determine synapse-scale connectivity by virtually reconstructing a cortical microcircuit and comparing it to a mammalian sample. These principles now make it possible to predict the locations of synapses in the neocortex. Contact: Lionel Pousaz Public Release: 14-Sep-2012
New NIH/NHGRI grants to harness nanoscale technologies to cut DNA sequencing costs Grants of almost $19 million will help to develop technologies to dramatically reduce the cost of DNA sequencing, the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, announced today. Contact: Omar McCrimmon Public Release: 13-Sep-2012
Study of giant viruses shakes up tree of life A new study of giant viruses supports the idea that viruses are ancient living organisms and not inanimate molecular remnants run amok, as some scientists have argued. The study reshapes the universal family tree, adding a fourth major branch to the three that most scientists agree represent the fundamental domains of life. Contact: Diana Yates Public Release: 13-Sep-2012
Gladstone scientists map the genomic blueprint of the heart Scientists at the Gladstone Institutes have revealed the precise order and timing of hundreds of genetic "switches" required to construct a fully functional heart from embryonic heart cells -- providing new clues into the genetic basis for some forms of congenital heart disease. Contact: Anne Holden Public Release: 12-Sep-2012
Weizmann Institute's mathematical model may lead to safer chemotherapy The study explains why certain patients develop severe infections after chemotherapy and points to ways of averting this side-effect. Contact: Yivsam Azgad Public Release: 9-Sep-2012
Uncovering the genome's regulatory code A new, automated method for mapping protein-DNA interactions may lead to advances in personalized medicine. Contact: Yivsam Azgad Public Release: 6-Sep-2012
2 pioneering plant genomics efforts given a funding boost by National Science Foundation With research in plant biology "at a tipping point," in the words of a leading investigator, two pathbreaking efforts by scientists interested in making comparisons across and within sequenced plant genomes -- called Gramene and Plant Reactome -- have been given a significant funding boost and vote of confidence from the National Science Foundation. Contact: Peter Tarr Public Release: 6-Sep-2012
Storm of 'awakened' transposons may cause brain-cell pathologies in ALS, other illnesses A team of neuroscientists and informatics experts at Cold Spring Harbor Laboratory reports important progress in an effort to understand the relationship between transposons – sequences of DNA that can jump around within the genome, potentially causing great damage – and mechanisms involved in serious neurodegenerative disorders including ALS, FTLD (frontotemporal lobar degeneration) and Alzheimer's disease. Contact: Peter Tarr Public Release: 6-Sep-2012
Human genome far more active than thought The GENCODE Consortium has found 50 percent more genes than previously thought. Among their discoveries, the team describe more than 10,000 novel genes, identify genes that have 'died' and others that are being resurrected. Contact: Aileen Sheehy Public Release: 5-Sep-2012
Grant funds West Coast Metabolomics Center With a $9.3 million start-up grant from the National Institutes of Health, UC Davis plans to open the West Coast Metabolomics Center, a high-tech consortium of research and service laboratories that will help scientists better understand and develop more effective treatments for complex diseases like diabetes, cancer and atherosclerosis. Contact: Andy Fell Public Release: 5-Sep-2012
DNA sequences need quality time too - guidelines for quality control published DNA sequence data have become an indispensable source of information in biology, finding diverse uses such as molecular species identification and the exploration of biodiversity in complex environments like soil and seawater. Many research programs enabled by such molecular data would have seemed impossible just a few years ago, and the unparalleled resolution obtained through DNA sequences adds further to their attractiveness in biological research. Contact: Dr. Henrik Nilsson Public Release: 5-Sep-2012
In massive genome analysis ENCODE data suggests 'gene' redefinition As part of a huge collaborative effort called ENCODE (Encyclopedia of DNA Elements), a research team at CSHL has analyzed all the RNA messages, called transcripts, produced within human cells. They show that three-quarters of the genome is capable of being transcribed, indicating that nearly all of our genome is dynamic and active. This raises exciting new possibilities for research into complex genetic diseases. Contact: Edward Brydon Public Release: 5-Sep-2012
UMASS Medical School faculty annotate human genome for ENCODE project The first comprehensive decoding and annotation of the human genome is being published today by the ENCyclopedia Of DNA Elements (ENCODE) project, an international consortium of scientists from 32 institutions, including the University of Massachusetts Medical School. The groundbreaking ENCODE discovery appears in a set of 30 papers in Nature, Genome Research and Genome Biology. Contact: Jim Fessenden Public Release: 5-Sep-2012
Huge human gene study includes Penn State University research The first integrated understanding of how the human genome functions will be published this week -- the triumphant result of a collaborative five-year project called ENCODE, involving more than 440 researchers working in 32 labs worldwide. Penn State's contribution involves using the new ENCODE data to help explain how genetic variants that do not affect the structure of encoded proteins could affect a person's susceptibility to disease. Contact: Barbara K. Kennedy Public Release: 5-Sep-2012
Fast forward for biomedical research: ENCODE scraps the junk An international team of researchers has revealed that much of what has been called 'junk DNA' in the human genome is actually a massive control panel with millions of switches regulating the activity of our genes. Discovered by hundreds of scientists working on the ENCODE Project, the new information is so comprehensive and complex that it has given rise to a new publishing model. Contact: Mary Todd Bergman Public Release: 5-Sep-2012
The ENCODE Project publishes new genomic insights in special issue of Genome Research Genome Research publishes online and in print today a special issue dedicated to The ENCODE (ENCyclopedia Of DNA Elements) Project, whose goal is to characterize all functional elements in the human genome. The entire issue will be freely available online on Sept. 6 to coordinate with additional ENCODE Consortium publications in Nature, Genome Biology, and other journals. Contact: Peggy Calicchia Public Release: 4-Sep-2012
Vitamin D supplements do not improve cholesterol as previous research suggested A team of scientists from Rockefeller University has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. Contact: Joseph Bonner Public Release: 4-Sep-2012
Eurofins MWG Operon reinforces NGS capability with Illumina HiSeq 2500 and Illumina MiSeq Eurofins MWG Operon, one of the pioneers and key providers of next generation sequencing (NGS), has added an Illumina HiSeq 2500 and an Illumina MiSeq sequencer to its fleet of NGS sequencers. Contact: Dr. Georg Gradl Public Release: 4-Sep-2012
Study points to new target for cancers resistant to Iressa and Herceptin A more-sensitive method to analyze protein interactions has uncovered a new way that cancer cells may use the cell-surface molecule HER3 to drive tumor progression following treatment with HER1 and HER2 inhibitors. This study shows that HER3 could be up to 10 times more effective than HER2, the target for Herceptin, in recruiting the proteins that drive the rapid proliferation, enhanced survival and distant spread of cancer. Contact: John Easton Public Release: 3-Sep-2012
Anchoring proteins influence glucose metabolism and insulin release Scientists from the United States and Sweden have discovered a new control point that could be important as a drug target for the treatment of diabetes and other metabolic diseases. Contact: Barry Whyte Public Release: 3-Sep-2012
Mass spec makes the clinical grade A new mass spectrometry-based test identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online. The head-to-head comparison using blood samples from cancer patients measured biomarkers, proteins whose presence identifies a disease or condition. The technique should be able to speed up development of protein-specific diagnostic tests and treatment. Contact: Mary Beckman Public Release: 31-Aug-2012
BUSM researchers find potential key to halt progression, reverse damage from emphysema A study led by researchers at Boston University School of Medicine has shown that a compound used in some skin creams may halt the progression of emphysema and reverse some of the damage caused by the disease. When the compound Gly-His-Lys was applied to lung cells from patients with emphysema, normal gene activity in altered cells was restored and damaged aspects of cellular function were repaired. Contact: Jenny Eriksen Public Release: 30-Aug-2012
Rice, MD Anderson scientists probe mystery of operon evolution New research this week in PLOS Computational Biology suggests a possible explanation for the organization of operons, jointly controlled clusters of genes that evolved in bacterial chromosomes. Operons, which are found in the chromosomes of bacteria but not in more advanced organisms, have puzzled biologists since their discovery in the 1960s. The new study suggests operons evolved as a means of reducing "noise" in biochemical signal processing. Contact: Jade Boyd
Showing releases 76-100 out of 344. << < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>
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