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Disease in the Developing World

News Releases

Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 1249.

1 | 2 | 3 | 4 | 5 > >>

Public Release: 23-Jun-2016
Nature
Antibodies that are effective against both dengue and Zika viruses
Scientists from the Institut Pasteur and the CNRS, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal vaccine that offers simultaneous protection against dengue and Zika virus disease.
European Framework Programme DENFREE, Integrative Biology of Emerging Infectious Diseases LabEx, FlaviStem Grant

Contact: Myriam Rebeyrotte
presse@pasteur.fr
Institut Pasteur

Public Release: 23-Jun-2016
New England Journal of Medicine
Malaria -- a mapping of artemisinin resistance confirms that resistance is confined to Asia
The first global mapping of artemisinin resistance (the KARMA study) has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa. Led by researchers from both the Institut Pasteur in Paris and the Institut Pasteur in Cambodia, KARMA gathers a large consortium of institutions including 13 members of the Institut Pasteur International Network.
World Health Organization

Contact: Myriam Rebeyrotte
presse@pasteur.fr
Institut Pasteur

Public Release: 23-Jun-2016
Cancer Prevention Research
Broccoli sprout extract may protect against oral cancer recurrence
Potent doses of broccoli sprout extract activate a 'detoxification' gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a 'green chemoprevention' trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter. It is the first study demonstrating that the extract protects against oral cancer, with the results of human, animal and laboratory tests reported today.
NIH/National Cancer Institute, Lewis B. and Dorothy Cullman Foundation

Contact: Allison Hydzik
hydzikam@upmc.edu
412-647-9975
University of Pittsburgh Schools of the Health Sciences

Public Release: 23-Jun-2016
PLOS Neglected Tropical Diseases
Evaluation of commercially sold rapid rabies tests reveals serious problems with accuracy
Rabies virus (RABV) transmitted by dogs is responsible for an estimated 60,000 human deaths per year, especially in Asia and Africa. A study published in PLOS NTDs reports that six commercially available rapid rabies tests -- which could make testing dogs much easier -- fail to reproducibly yield accurate results.
Friedrich Loeffler Institute

Contact: Conrad Freuling
Conrad.Freuling@fli.bund.de
49-038-351-71660
PLOS

Public Release: 22-Jun-2016
Scientific Reports
New targeted drug effectively dissolves blood clots, has fewer side effects
The main objective of emergency assistance in critical conditions associated with the blockage of blood vessels is to quickly dissolve the clot. To this end, Russian scientists have developed a magnetically controlled drug that can be condensed on a blood clot by means of a magnetic field and can dissolve clots up to 4,000 times more efficiently than ordinary enzyme-based drugs. The new study will also help reduce drug dosage, thus avoiding numerous side effects.
Russian Science Foundation

Contact: Dmitry Malkov
dvmalkov@corp.ifmo.ru
7-953-377-5508
ITMO University

Public Release: 21-Jun-2016
Vaccine
Drones could be cheaper alternative to delivering vaccines in developing world
Using unmanned drones to deliver vaccines in low- and middle-income countries may save money and improve vaccination rates, new research led by the Johns Hopkins Bloomberg School of Public Health and the Pittsburgh Supercomputing Center suggests.
Bill and Melinda Gates Foundation, Agency for Healthcare Research and Quality, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Stephanie Desmon
sdesmon1@jhu.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health

Public Release: 20-Jun-2016
Just how gestational diabetes puts babies at lifelong risk for cardiovascular disease, under study
Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how.
NIH/National Institute of Child Health and Human Development

Contact: Toni Baker
tbaker@augusta.edu
706-721-4421
Medical College of Georgia at Augusta University

Public Release: 20-Jun-2016
Antimicrobial Agents and Chemotherapy
Stealth nanocapsules kill Chagas parasites in mouse models
Lychnopholide, a substance isolated from a Brazilian plant, and formulated as part of 'nanocapsules' cured more than half of a group of mice that had been infected experimentally with Chagas disease parasites. 'Chagas disease affects millions of people, mainly in poor rural areas of 21 Latin American countries,' said Marta de Lana, Ph.D.

Contact: Aleea Khan
communications@asmusa.org
202-942-9365
American Society for Microbiology

Public Release: 16-Jun-2016
Journal of Health Care Finance
'Disease outbreak guarantees' -- A proposed mechanism for enhancing public health capacity
What if private companies could obtain some coverage to protect their foreign investments in developing countries against crippling infectious disease outbreaks such as Ebola? The possible path to offering disease outbreak guarantees is an idea being posed by two global health researchers who suggest that a mechanism for establishing such an instrument could be tied to public health investments.

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 16-Jun-2016
PLOS Neglected Tropical Diseases
Cholera vaccine study in Haiti suggests problems with current booster regimen
Cholera outbreaks are on the rise. To prevent and control them, three oral cholera vaccines are currently approved by WHO. A study published in PLOS NTDs examining the immune response to one of them in Haitian adults finds that while the first vaccine round elicits a strong cholera-specific response in the mucosa (the first point of contact with the cholera pathogen), the booster dose after 2 weeks does not appear to stimulate the immune system further.

Contact: Jason B. Harris
jbharris@mgh.harvard.edu
617-726-3812
PLOS

Public Release: 16-Jun-2016
PLOS Pathogens
Mosquito saliva increases disease severity following dengue virus infection
Insects transmit diseases when, probing for blood vessels, they inject saliva together with viral, bacterial, or parasitic pathogens into the skin of mammalian hosts. A study in mice published on June 16, 2016 in PLOS Pathogens suggests a critical role of mosquito saliva in the outcome of dengue virus infection.

Contact: Michael Schmid
michael.alex.schmid@gmail.com
PLOS

Public Release: 15-Jun-2016
Bioinformatics
Personalized medicine will employ computer algorithms
Russian scientists have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice. Using the algorithm to compare the microflora of a healthy person with the microflora of a patient, specialists would be able to detect previously unknown pathogens and their strains, which can aid the development of personalized medicine. The results of the study have been published in Bioinformatics.
The Government of Russian Federation, Russian Scientific Foundation

Contact: Dmitry Malkov
dvmalkov@corp.ifmo.ru
7-953-377-5508
ITMO University

Public Release: 15-Jun-2016
Celgene joins DNDi's 'Drug Discovery Booster'
The biopharmaceutical company Celgene has become the fifth company to join the 'Neglected Tropical Diseases Drug Discovery Booster' consortium, a new initiative to accelerate and cut the cost of early stage drug discovery for two of the world's most neglected diseases, leishmaniasis and Chagas disease.

Contact: Violaine Dallenbach
vdallenbach@dndi.org
41-794-241-474
Drugs for Neglected Diseases Initiative

Public Release: 14-Jun-2016
Journal of the American Heart Association
As Olympics near, study finds low levels of physical activity in Brazil
A large study confirms that physical activity provides Brazilians with significant cardio-metabolic health benefits, but reports that fewer than three in 10 participants are active.
Ministry of Health of Brazil, Brazilian Council of Research, University of São Paolo, American Heart Association, Brown University's Brazil Initiative

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 14-Jun-2016
Clinical Infectious Diseases
Antibiotics against severe salmonella infections in Africa increasingly ineffective
Salmonella infections in the bloodstream, caused by Salmonella enterica bacteria, are still the cause of many deaths in southern regions and Southeast Asia. Children between the age of two and five years are particularly affected. Treating these infections could become a growing problem owing to increasing antibiotic resistance. DZIF scientists from the Bernhard Nocht Institute for Tropical Medicine have now confirmed that even the newer generations of antibiotics are becoming less and less effective.

Contact: Jürgen May
may@bnitm.de
49-404-281-8369
German Center for Infection Research

Public Release: 14-Jun-2016
Microbial Genomics
Genome sequencing helps determine end of tuberculosis outbreak
Using genome sequencing, researchers from the University of British Columbia, along with colleagues at the Imperial College in London, now have the ability to determine when a tuberculosis outbreak is over.

Contact: Katherine Came
katherine.came@ubc.ca
604-822-0530
University of British Columbia

Public Release: 14-Jun-2016
eLife
New plant engineering method could help fill demand for crucial malaria drug
A new and inexpensive technique for mass-producing the main ingredient in the most effective treatment for malaria, artemisinin, could help meet global demands for the drug, according to a study to be published in the journal eLife.
European Research Council, Max-Planck-Gesellschaft

Contact: Emily Packer
e.packer@elifesciences.org
eLife

Public Release: 13-Jun-2016
PLOS ONE
Topical application of antiretroviral drug combination prevents transmission of (S)HIV
Findings published last week in the journal PLOS ONE confirm that researchers from the Oak Crest Institute of Science have demonstrated for the first time that two powerful antiretroviral drugs can provide complete protection against HIV when delivered topically by a sustained release intravaginal ring (IVR) device. The combination of tenofovir disoproxil fumarate and emtricitabine delivered at independently controlled rates via the pod-IVR was successful at preventing SHIV162p3 infection for over four months.

Contact: Dr. Marc M. Baum
info@oak-crest.org
626-817-0883
Oak Crest Institute of Science

Public Release: 10-Jun-2016
FDA approves vaccine for cholera
In a milestone years in the making, a vaccine to prevent cholera was approved today by the FDA. The vaccine, Vaxchora, is the only approved vaccine in the US for protection against cholera.

Contact: David Kohn
dkohn@som.umaryland.edu
410-706-7590
University of Maryland School of Medicine

Public Release: 10-Jun-2016
The Open Nursing Journal
An investigation of nurses' job satisfaction in a private hospital and its correlates
Job satisfaction and its impact on staff performance, absenteeism, retention, and turnovers in health care services has been a topic of global interest over decades.

Contact: Faizan ul Haq
faizan@benthamscience.org
Bentham Science Publishers

Public Release: 8-Jun-2016
npj Microgravity
Switched-on Salmonella: Fluid forces guide disease traits of multidrug-resistant bacteria
In new research appearing in the Nature Publishing Group journal npj Microgravity, Cheryl Nickerson, Ph.D., and her colleagues explore the effects of physiological fluid shear on ST313 -- a particularly dangerous type of Salmonella, which is resistant to multiple antibiotics and currently ravaging regions of sub-Saharan Africa.

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University

Public Release: 8-Jun-2016
Antimicrobial Agents and Chemotherapy
Modeling the correct doses for disease-fighting drugs
Publishing earlier this week in the American Society for Microbiology's Antimicrobial Agents and Chemotherapy, Brad Reisfeld, associate professor in Colorado State University's Department of Chemical and Biological Engineering, has described a new computational model for optimizing dosing for the tuberculosis drug Rifapentine.

Contact: Anne Ju Manning
anne.manning@colostate.edu
970-491-7099
Colorado State University

Public Release: 8-Jun-2016
Journal of Neuroscience
Metabolite of multiple sclerosis drug could be safe, effective therapy for Parkinson's disease
The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say.

Contact: Toni Baker
tbaker@augusta.edu
706-721-4421
Medical College of Georgia at Augusta University

Public Release: 7-Jun-2016
Proceedings of the National Academy of Sciences
Pneumococcal vaccine watches bacteria, strikes only when needed
Conventional vaccines indiscriminately destroy bacteria and other disease-causing agents. The approach works, but there is growing concern that it creates opportunity other pathogens to harm the body -- similar to antibiotic resistance resulting in new and more potent pathogens. A new, protein-based pneumococcal vaccine takes a different approach. It allows pneumonia-causing bacteria to colonize in the body and -- like a nightclub bouncer -- swings into action only if the bacteria becomes harmful.
National Institutes of Health, Swedish Medical Research Council, Arthur A. Schomburg Fellowship Program at the University at Buffalo

Contact: Cory Nealon
cmnealon@buffalo.edu
716-645-4614
University at Buffalo

Public Release: 7-Jun-2016
Biology Letters
Sexual transmission of Ebola likely to impact course of outbreaks
Sexual transmission of the Ebola virus could have a major impact on the dynamics of the disease, potentially reigniting an outbreak that has been contained by public health interventions, according to research by University of Georgia ecologists just published in the Royal Society journal Biology Letters. The potential for sexual transmission is high for three to four months after the virus has been cleared from the bloodstream, and possible for an average of seven months.
NIH/National Institute of General Medical Sciences, National Science Foundation

Contact: Stephanie Schupska
schupska@uga.edu
706-542-6927
University of Georgia

Showing releases 1-25 out of 1249.

1 | 2 | 3 | 4 | 5 > >>