EurekAlert! InContext Modules

Public Release: 2-Aug-2013

Journal of Biological Chemistry
New findings could influence the development of therapies to treat dengue disease
New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

Public Release: 1-Aug-2013

Biomicrofluidics
Catching cancer early by chasing it
Reaching a clinic in time to receive an early diagnosis for cancer -- when the disease is most treatable -- is a global problem. And now a team of Chinese researchers proposes a global solution: have a user-friendly diagnostic device travel to the patient, anywhere in the world.

Public Release: 1-Aug-2013
Boston Medical Center and BU School of Medicine partner with Jawaharlal Institute to study TB
Boston Medical Center and Boston University School of Medicine are partnering with the Jawaharlal Institute of Postgraduate Medical Education and Research to study tuberculosis. This research is supported by a five-year, $2.5 million grant from the Indo-US Vaccine Action Program.

the Indo-U.S. Vaccine Action Program

Public Release: 1-Aug-2013

International Journal of Mobile Learning and Organisation
An app to lead the blind
A smartphone app that keeps track of your location and distance walked from home or hotel and warns you when you are likely to be caught out after dark has been developed by researchers in Pakistan to help sufferers of the debilitating disease night blindness. The app can also help travelers with the disease pinpoint hotels should they find themselves too far from base to get home safely.

Public Release: 30-Jul-2013

Child Development
Disabled children treated more harshly in developing world
Children with disabilities receive harsher punishment across the developing world, according to a new study based on interviews with nearly 46,000 caregivers in 17 low- to middle-income countries.

National Institutes of Health

Public Release: 30-Jul-2013

Child Development
Children with disabilities in developing countries at risk for harsher punishment
Children with disabilities who live in developing countries are more likely to experience harsh punishment than children without disabilities in those countries. It is estimated that 80 percent of those with a disability are living in low- or middle-income countries. Researchers looked at data from 46,000 parents and other caregivers of 2- to 9-year-olds in 17 low- and middle-income countries. They found that children with disabilities are especially vulnerable to abuse, exploitation, and violence.

NIH/Eunice Kennedy Shriver National Institute of Child Health

Public Release: 29-Jul-2013

Proceedings of the National Academy of Sciences
New modular vaccine design combines best of existing vaccine technologies
Boston Children's researchers develop new method of vaccine design -- Multiple Antigen Presentation System. It could speed new vaccine development for range of globally serious pathogens, infectious agents. Method permits rapid construction of new vaccines that bring together benefits of whole-cell and acellular or defined subunit vaccination and activate mulitple arms of the immune system simultaneously against one or more pathogens, generating robust immune protection with lower risk of adverse effects.

Boston Children's Hospital

Public Release: 28-Jul-2013

Nature Chemistry
Breakthrough in detecting DNA mutations could help treat tuberculosis, cancer
Researchers at the University of Washington and Rice University have developed a new method that can look at a specific segment of DNA and pinpoint a single mutation, which could help diagnose and treat diseases such as cancer and tuberculosis.

Public Release: 25-Jul-2013

Clinical Infectious Diseases
Miriam researcher helps develop global hepatitis C recommendations for injection-drug users
Dr. Lynn Taylor from The Miriam Hospital in Providence, RI was the only US researcher invited to join an expert panel to develop the first international recommendations for treating hepatitis C in people who inject drugs. She also wrote a separate paper calling for improved HCV care for individuals who are infected with both hepatitis C and HIV and also inject drugs.

Public Release: 24-Jul-2013

Clinical Infectious Diseases
Combining treatments for people who inject drugs is the first step towards eliminating hepatitis C
The burden of liver disease could be dramatically reduced by scaling up the combination of interventions for hepatitis C infection among people who inject drugs according to University of Bristol researchers. The findings, published today [24 July], form part of new global recommendations on treating the virus.

Public Release: 23-Jul-2013

Applied and Environmental Microbiology
Natural pest control protein effective against hookworm: A billion could benefit
A benign crystal protein, produced naturally by bacteria and used as an organic pesticide, could be a safe, inexpensive treatment for parasitic worms in humans and provide effective relief to over a billion people around the world. Researchers from the University of California, San Diego, La Jolla, CA, report on this potentially promising solution in a study published ahead of print in the journal Applied and Environmental Microbiology.

Public Release: 23-Jul-2013

Cell Host & Microbe
Mount Sinai researchers identify vulnerabilities of the deadly Ebola virus
Disabling a protein in Ebola virus cells can stop the virus from replicating and infecting the host, according to researchers from the Icahn School of Medicine at Mount Sinai.

Public Release: 23-Jul-2013
University of Tennessee professors explore end-of-life needs for HIV/AIDS patients
Approximately 10,000 Americans die with an HIV/AIDS diagnosis each year, and many of these patients lack access to the care they need at the end of their lives. This is especially true for those who live in the Appalachian region. A group of nursing professors at the University of Tennessee, Knoxville, is embarking on a study to try to change this.

National Institutes of Health

Public Release: 22-Jul-2013

Proceedings of the National Academy of Sciences
Off-grid sterilization with Rice U.'s 'solar steam'
Rice University nanotechnology researchers have unveiled a solar-powered sterilization system that could be a boon for more than 2.5 billion people who lack adequate sanitation. The "solar steam" sterilization system uses nanomaterials to convert as much as 80 percent of the energy in sunlight into germ-killing heat. The technology is described online in the Proceedings of the National Academy of Sciences Early Edition.

Bill & Melinda Gates Foundation, Welch Foundation

Public Release: 22-Jul-2013

mBio
Study lays groundwork for norovirus anti-viral treatments
There's no vaccine to prevent norovirus, or drugs to treat the pesky virus that sickens millions each year and is known to complicate cruise ship vacations. But a first ever small animal model created at the University of Michigan Medical School provides a new tool to develop anti-viral treatments.

National Institutes of Health

Public Release: 19-Jul-2013

PLOS Currents
Researchers describe potential for MERS coronavirus to spread internationally
The life-threatening MERS coronavirus that has emerged in the Middle East could spread faster and wider during two international mass gatherings involving millions of people in the next few months, according to researchers who describe the most likely pathways of international spread based upon worldwide patterns of air travel.

Canadian Institutes of Health Research, US Centers for Disease Control and Prevention

Public Release: 19-Jul-2013

Science Translational Medicine
The genetic key to conquering cholera
Researchers have long understood that genetics can play a role in how susceptible people are to contracting cholera, but a team of Harvard scientists is now uncovering evidence of genetic changes that might also help protect some people from contracting the deadly disease.

Public Release: 17-Jul-2013

Nutrition for Growth Summit
Conflict threatens global nutrition progress, new report warns
Major progress in tackling child undernutrition in some of the world's toughest countries is under threat as military and security funding takes precedence, a new report from aid agency World Vision warns.

Public Release: 16-Jul-2013

Health Affairs
Health Affairs July issue contains global innovation studies from India And Brazil
Two new studies, in Health Affairs July 2013 issue, describe health success stories outside the US.

Public Release: 16-Jul-2013
Research leads to affordable technology to fight mosquito-borne diseases
Technology that hampers mosquitoes' host-seeking behavior, identified at the University of California, Riverside in 2011, has led to the development of the world's first product that blocks mosquitoes' ability to efficiently detect carbon dioxide, their primary method of tracking human blood meals.

Bill and Melinda Gates Foundation, National Institutes of Health

Public Release: 12-Jul-2013

PLOS Neglected Tropical Diseases
Exploring gender dimensions of treatment programs for neglected tropical diseases in Uganda
Males and females face different challenges in accessing treatment for neglected tropical diseases, according to a new study from researchers at the University of Toronto Dalla Lana School of Public Health, Uganda Ministry of Health and Imperial College London. The study, published by PLOS Neglected Tropical Diseases on July 11, explores the role of gender in access to treatment in the Uganda National Neglected Tropical Disease Control Program.

Public Release: 11-Jul-2013

Nucleic Acid Therapeutics
New therapeutic strategy targets dengue virus using artificial microRNAs
Mosquito-borne dengue viruses cause an estimated 50 million cases of human dengue fever a year and are a significant public health threat worldwide.

Public Release: 11-Jul-2013
3 neglected-disease treatments newly added to WHO Essential Medicines List for paediatric use
This week the World Health Organization (WHO) released its newly updated 4th WHO Model List of Essential Medicines for Children, in which three treatments developed by the Drugs for Neglected Diseases initiative and its partners have now been included. One treatment was also added to the 18th WHO Model List of Essential Medicines for adults.

Public Release: 10-Jul-2013

Molecular Biology and Evolution
Malaria in the Americas presents a complex picture
In a new study, Ananias Escalante and an international team explore the genetic diversity of malarial parasite P. vivax in the Americas and other areas of the world. The study shows greater genetic diversity for P. vivax compared with earlier studies and points to plausible routes of malarial introduction into the New World.

Public Release: 10-Jul-2013
University of North Carolina receives $8 million grant to improve safe motherhood in Malawi
The University of North Carolina at Chapel Hill has received a five-year, $8 million grant from the Bill & Melinda Gates Foundation to improve maternal and infant health and save the lives of mothers and infants in Malawi by strengthening the President's Maternal Health and Safe Motherhood Initiative.

Bill & Melinda Gates Foundation


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