EurekAlert! InContext Modules

Public Release: 2-Feb-2012

Osteoporosis International
Southampton research shows early bone growth linked to bone density in later life
Researchers from the University of Southampton, in collaboration with a research group in Delhi, India, have shown that growth in early childhood can affect bone density in adult life, which could lead to an increased risk of developing bone diseases like osteoporosis.

British Heart Foundation

Public Release: 2-Feb-2012

Science Translational Medicine
Potential new treatment identified for leishmaniasis
Researchers at the University of Dundee have identified fexinidazole as a possible, much-needed, new treatment for the parasitic disease visceral leishmaniasis.

Wellcome Trust

Public Release: 2-Feb-2012

Cell
'Goldilocks' gene could determine best treatment for TB patients
Tuberculosis patients may receive treatments in the future according to what version they have of a single 'Goldilocks' gene, says an international research team from Oxford University, King's College London, Vietnam and the USA.

Wellcome Trust

Public Release: 2-Feb-2012

Lancet
Malaria kills nearly twice as many people than previously thought, but deaths declining rapidly
Malaria is killing more people worldwide than previously thought -- 1.2 million -- but the number of deaths has fallen rapidly as efforts to combat the disease have ramped up, according to new research from the Institute for Health Metrics and Evaluation at the University of Washington. IHME researchers say that deaths from malaria have been missed by previous studies because of the assumption that the disease mainly kills children under age five.

Bill and Melinda Gates Foundation

Public Release: 31-Jan-2012

Arthritis Care & Research
Poor neighborhoods suffer higher incidence of arthritis
People living in poor neighborhoods have a higher rate and risk of arthritis - one of the most common causes of disability in the developed world.

Public Release: 31-Jan-2012
NIH to join multi-center clinical trial of new tuberculosis vaccine
The National Institute of Allergy and Infectious Diseases, part of the United States National Institutes of Health, has joined as a partner for a Phase II proof-of-concept clinical trial of a tuberculosis vaccine candidate jointly developed by Aeras and Dutch biopharmaceutical company Crucell. This is thee first time that NIH is leveraging its HIV/AIDS clinical trial networks to advance a tuberculosis vaccine candidate.

Public Release: 27-Jan-2012

Journal of the Federation of American Societies for Experimental Biology
Study offers new information for flu fight
Influenza virus can rapidly evolve from one form to another, complicating the effectiveness of vaccines and anti-viral drugs used to treat it. By first understanding the complex host cell pathways that the flu uses for replication, University of Georgia researchers are finding new strategies for therapies and vaccines, according to a study published in the January issue of the Journal of the Federation of American Societies for Experimental Biology.

Public Release: 27-Jan-2012

Structure
Research on vitamins could lead to the design of novel drugs to combat malaria
New research by scientists at the University of Southampton could lead to the design of more effective drugs to combat malaria.

Public Release: 27-Jan-2012
European Research Council supports search for regulators of tissue damage
The European Research Council has awarded Miguel Soares and his team at the Instituto Gulbenkian de Ciência in Portugal an Advanced Grant of just over 2,2 million euros, to investigate the capacity that an infected individual has to limit the extent of tissue damage caused by different pathogens. This line of research should identify and pave the way to the development of new therapeutic interventions for various infectious diseases.

European Research Council

Public Release: 27-Jan-2012

Journal of Biological Chemistry
Scientists reveal how cholera bacterium gains a foothold in the gut
A team of biologists at the University of York has made an important advance in our understanding of the way cholera attacks the body. The discovery could help scientists target treatments for the globally significant intestinal disease which kills more than 100,000 people every year.

Biotechnology and Biological Sciences Research Council

Public Release: 25-Jan-2012

Journal of Biological Chemistry
Researchers discover method to unravel malaria's genetic secrets
Researchers at National Jewish Health have devised a technique to overcome a genetic oddity of Plasmodium falciparum, the major cause of human malaria, which has stymied research into the organism's genes. The technique opens the door to genetic discovery for the entire organism, which should foster a greater understanding of the parasite, and facilitate discovery of new medications for a disease that infects 200 million people and kills nearly 700,000 every year.

National Institutes of Health, Burroughs Welcome Fund

Public Release: 25-Jan-2012
Young adults responded well to swine flu
About one in five young adults in their late 30's received a flu shot during the 2009-2010 swine flu epidemic, a University of Michigan study released today says. But about 65 percent were at least moderately concerned about the flu, and nearly 60 percent said they were following the issue very or moderately closely.

Public Release: 24-Jan-2012
$5.8 million Gates grant targets child-killing bacteria diseases in Africa
Bacteria infections -- most of which are preventable via vaccines readily available in the developed world -- and not malaria are the leading cause of death for children in sub-Saharan Africa. A new Michigan State University project based in Nigeria and funded by a $5.8 million grant aims to help prevent these diseases by collecting local data on the ailments, spurring vaccine use and development.

Bill and Melinda Gates Foundation

Public Release: 24-Jan-2012
Portuguese science scores high with American funder
Five of the 28 scientists considered "people who, 10 years from now, will be the scientific leaders in their countries," by the Howard Hughes Medical Institute, are working in Portugal. HHMI's newest awardees were chosen from 760 candidates, from 18 countries. Each researcher secures $650,000 in funding over a five-year period to carry out research in such diverse areas as neuroscience, parasitology, aging and bacterial communication.

Howard Hughes Medical Institute

Public Release: 24-Jan-2012

PLOS Medicine
Availability and use of sanitation reduces by half the likelihood of parasitic worm infections
Access to sanitation facilities, such as latrines, reduces by half the risk of becoming infected by parasitic worms that are transmitted via soil according to a study published in this week's PLoS Medicine.

Public Release: 23-Jan-2012

Malaria Journal
New malaria maps to guide battle against the disease
A new suite of malaria maps has revealed in unprecedented detail the current global pattern of the disease, allowing researchers to see how malaria has changed over a number of years.

Wellcome Trust

Public Release: 19-Jan-2012

Global Risk Forum's One Health Summit 2012
Revamping HIV-prevention programs in the Caribbean
While global attention to HIV/AIDS remains strong, a lack of focus on prevention strategies is stonewalling health experts in many developing nations, specifically in the Caribbean. By adopting a new approach to HIV prevention, Michigan State University's Institute of International Health is hoping to turn the tide on new infections on the island of Hispaniola, which accounts for nearly 75 percent of the Caribbean's AIDS cases.

Public Release: 19-Jan-2012

Science
Carnegie Mellon study reveals potential of manganese in neutralizing deadly Shiga toxin
Carnegie Mellon researchers have discovered that manganese, an element commonly found in nature, might provide a way to neutralize the potentially lethal effects Shiga toxin. New results published in the Jan. 20 issue of Science could pave the way for future research aimed at creating an inexpensive treatment for infections caused by bacteria that produce the Shiga toxin. Currently there is no treatment for such infections that afflict more than 150 million people each year, resulting in more than one million deaths worldwide.

National Institutes of Health, American Heart Association

Public Release: 18-Jan-2012

Journal of Development Economics
Study shows connection between birth weights and armed conflict
A new study shows pregnant women exposed to armed conflict have a higher risk of giving birth to underweight babies.

Public Release: 18-Jan-2012

Cell Host & Microbe
Unveiling malaria's 'cloak of invisibility'
The discovery by researchers from the Walter and Eliza Hall Institute of a molecule that is key to malaria's 'invisibility cloak' will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system.

National Health and Medical Research Council of Australia, Victorian Government

Public Release: 18-Jan-2012
New book, 'The Creative Destruction of Medicine,' outlines digital health care revolution
Health care is on the verge of a medical revolution, writes author Dr. Eric Topol in his new book, "The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care" (Basic Books, available in hardcover Feb. 1, 2012). In his book, Topol introduces medicine's digital future and explores how digitization will fundamentally change the medical field for both professionals and patients. Smart phones, wireless technology and social networking are fueling this shakeup.

Public Release: 17-Jan-2012

Nature Genetics
Genetic code cracked for a devastating blood parasite
Scientists have cracked the genetic code and predicted some high priority drug targets for the blood parasite Schistosoma haematobium, which is linked to bladder cancer and HIV/ AIDS and causes the insidious urogenital disease schistosomiasis haematobia in more than 112 million people in Africa.

Australian Research Council, BGI-Shenzhen, National Health and Medical Research Council

Public Release: 17-Jan-2012

Malaria Journal
Counterfeit and substandard anti-malaria drugs threaten crisis in Africa, experts warn
Hopes of at last controlling malaria in Africa could be dashed by the emergence of poor quality and fraudulent anti-malarial medicines, warn experts writing in the Malaria Journal. Unless urgent action is taken both within Africa and internationally, they argue, millions of lives could be put at risk.

Wellcome Trust

Public Release: 17-Jan-2012

Lancet Infectious Diseases
Canadian-led research team develop new model to anticipate disease outbreaks at 2012 Olympics
A research team led by St. Michael's Hospital's Dr. Kamran Khan is teaming up with British authorities to anticipate and track the risk for an infectious disease outbreak at the London Olympics this summer.

Public Release: 17-Jan-2012

Angewandte Chemie International
Anti-malaria drug synthesized with the help of oxygen and light
In future it should be possible to produce the best anti-malaria drug, artemisinin, more economically and in sufficient volumes for all patients.


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