Public Release: 19-Nov-2015
Journal of Controlled Release Nanocarriers may carry new hope for brain cancer therapy
Berkeley Lab researchers have developed a new family of nanocarriers, called '3HM,' that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer known as glioblastoma multiforme.
National Institutes of Health
Public Release: 17-Nov-2015
PLOS ONE Scientists find bone protein inhibits prostate cancer invasion
Scientists from Lawrence Livermore National Laboratory in collaboration with researchers from University of California campuses at Merced and Davis have found that a secreted protein predominantly expressed in bone inhibits prostate cancer metastasis to bone.
Public Release: 16-Nov-2015 Pacific Northwest National Laboratory scientists win 5 R&D 100 awards
Technologies that impact cyber security, increase our ability to detect trace amounts of chemicals, convert sewage into fuel, view energy processes under real-world conditions and forecast future electric needs are among the newest R&D 100 award winners.
US Department of Energy, and others
Public Release: 2-Nov-2015
Nature Structural & Molecular Biology First complete pictures of cells' DNA-copying machinery
The first-ever images of the protein complex that unwinds, splits, and copies double-stranded DNA reveal something rather different from the standard textbook view. The electron microscope images, created by scientists at the US Department of Energy's Brookhaven National Laboratory with partners from Stony Brook University and Rockefeller University, offer new insight into how this molecular machinery functions.
National Institutes of Health
Public Release: 22-Oct-2015
Nature It takes a thief
The discovery by Berkeley Lab researchers of the structural basis by which bacteria are able to capture genetic information from viruses and other foreign invaders for use in their own immunological system holds promise for studying or correcting problems in human genomes.
National Science Foundation
Public Release: 21-Oct-2015 Berkeley Lab scientists to help build world's first total-body PET scanner
Scientists from Berkeley Lab have set out to help build the world's first total-body positron emission tomography scanner, a medical imaging device that could change the way cancers and other diseases are diagnosed and treated. The project is a consortium led by a UC Davis research team and includes scientists from Berkeley Lab and the University of Pennsylvania. It's supported by a recently announced five-year, $15.5 million Transformative Research Award from the National Institutes of Health.
National Institutes of Health
Public Release: 14-Oct-2015
SC15 Flowing toward red blood cell breakthroughs
A team led by Brown's George Karniadakis is using the Titan supercomputer at the Oak Ridge Leadership Computing Facility to simulate hundreds of millions of red blood cells in an attempt to develop better drug delivery methods and predictors to fight against tumor formation and sickle cell anemia.
US Department of Energy, National Institutes of Health
Public Release: 17-Aug-2015
Nature Scientists discover atomic-resolution details of brain signaling
Scientists have revealed never-before-seen details of how our brain sends rapid-fire messages between its cells. They mapped the 3-D atomic structure of a two-part protein complex that controls the release of signaling chemicals, called neurotransmitters, from brain cells. Understanding how cells release those signals in less than one-thousandth of a second could help launch a new wave of research on drugs for treating brain disorders.
Public Release: 13-Aug-2015 Sandia teams with industry to improve human-data interaction
Sandia National Laboratories and EyeTracking Inc. are researching computer information systems to make national security analysts better at getting meaningful information from large data sets coming in quickly in high-stress environments.
Public Release: 3-Aug-2015
Cell Host & Microbe Gut microbes affect circadian rhythms in mice, study says
A study including researchers from the US Department of Energy's Argonne National Laboratory and the University of Chicago found evidence that gut microbes affect circadian rhythms and metabolism in mice.
Public Release: 22-Jul-2015
Nature Long-sought discovery fills in missing details of cell 'switchboard'
A biomedical breakthrough in the journal Nature reveals never-before-seen details of the human body's cellular switchboard that regulates sensory and hormonal responses. The work is based on an X-ray laser experiment at the Department of Energy's SLAC National Accelerator Laboratory.
Public Release: 25-Jun-2015
ACS Environmental Science and Technology Argonne analysis shows increased carbon intensity from Canadian oil sands
The US Department of Energy's Argonne National Laboratory this week released a study that shows gasoline and diesel refined from Canadian oil sands has a higher carbon impact than fuels derived from conventional domestic crude sources.
Bioenergy Technologies Office and Vehicle Technologies Office within US Department of Energy's Office of Energy Efficiency and Renewable Energy
Public Release: 18-Jun-2015
Analytical and Bioanalytical Chemistry New tool on horizon for surgeons treating cancer patients
Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers from the Department of Energy's Oak Ridge National Laboratory and Brigham and Women's Hospital/Harvard Medical School.
Public Release: 16-Jun-2015
Chemical Physics Letters Unravelling the mysteries of carbonic acid
Berkeley Lab researchers report the first detailed characterization of the hydration structure of carbonic dioxide gas as it dissolves in water to form carbonic acid. Though carbonic acid exists for only a fraction of a second, it imparts a lasting impact on Earth's atmosphere and geology, and on the human body.
Public Release: 15-Jun-2015 Argonne confirms new commercial method for producing medical isotope
Argonne National Laboratory recently demonstrated a new commercial technique for producing molybdenum-99, a critical medical isotope used in millions of imaging procedures each year. The technique, developed by SHINE Medical Technologies, could help secure a domestic source for Mo-99.
National Nuclear Security Administration
Public Release: 9-Jun-2015 Argonne and ASU sign five-year research agreement
Argonne National Laboratory recently signed an agreement with Arizona State University that will facilitate a broad portfolio of research shared between the two institutions. The five-year memorandum of understanding (MOU) will establish a structure for Argonne and ASU to pursue novel research in areas including decision-making based on climate variability and uncertainty, the impacts of global population dynamics and urbanization, the challenges of renewable energy practices, and creating innovative solutions to problems in energy, education and sustainability.
Public Release: 26-May-2015
Journal of Synchrotron Radiation On-demand X-rays at synchrotron light sources
Researchers at Berkeley Lab's Advanced Light Source have developed an 'X-rays on demand' technique in which ALS users can have access to the X-ray beams they want without affecting beams for other users.
US Department of Energy Office of Science
Public Release: 14-May-2015
Nano Letters CLAIRE brings electron microscopy to soft materials
Berkeley Lab researchers, working at the Molecular Foundry, have invented a technique called 'CLAIRE' that extends the incredible resolution of electron microscopy to the noninvasive nanoscale imaging of soft matter, including biomolecules.
US Department of Energy Office of Science, National Science Foundation
Public Release: 13-May-2015
Blood Starving cancer cells instead of feeding them poison
An enzyme-drug that prevents the essential nutrient asparagine from reaching cancer cells seem an effective way to kill them, but that enzyme-drug also does away with the nutrient glutamine that all cells need. Now a simulation has directed the mutation of the enzyme so that, in wet labs, it left normal cells unharmed in Petri dishes and cancer cells dead in test tubes. Lab tests are underway with mice. If successful, human tests are next.
Sandia National Laboratories' Laboratory-Directed Research and Development
Public Release: 23-Apr-2015
Cell X-ray study may aid in designing better blood pressure drugs
An experiment at the Department of Energy's SLAC National Accelerator Laboratory has revealed in atomic detail how a hypertension drug binds to a cellular receptor that plays a key role in regulating blood pressure. The results could help scientists design new drugs that better control blood pressure while limiting side effects.
The Department of Energy's Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time.