Public Release: 7-Dec-2015 A cure for medical researchers' big data headache
Oak Ridge Graph Analytics for Medical Innovation (ORiGAMI), supplies researchers with an advanced data tool for literature-based discovery that has the potential to accelerate medical research and discovery. The result of collaboration between Oak Ridge National Laboratory and the US National Library of Medicine, ORiGAMI unites three emerging technologies that are shaping the future of health care: big data, graph computing, and the Semantic Web.
Public Release: 7-Dec-2015
Scientific Reports New clues for battling botulism
Scientists have discovered new details about how 'cloaking' proteins protect the toxin that causes botulism, a fatal disease caused most commonly by consuming improperly canned foods. That knowledge and the cloaking proteins themselves might now be turned against the toxin -- the deadliest known to humankind.
Defense Threat Reduction Agency, National Institutes of Health, DOE Office of Science
Public Release: 3-Dec-2015 Livermore Lab researchers use 3-D printing to build human physiology outside the body
The cardiovascular system is a complex web of tens of thousands of miles of arteries, capillaries and veins, branching throughout the body like tributaries of a great river. And now, researchers at Lawrence Livermore National Laboratory are recapitulating this intricate network using an emerging technology: 3-D bioprinting.
Public Release: 19-Nov-2015
Journal of Controlled Release Nanocarriers may carry new hope for brain cancer therapy
Berkeley Lab researchers have developed a new family of nanocarriers, called '3HM,' that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer known as glioblastoma multiforme.
National Institutes of Health
Public Release: 17-Nov-2015
PLOS ONE Scientists find bone protein inhibits prostate cancer invasion
Scientists from Lawrence Livermore National Laboratory in collaboration with researchers from University of California campuses at Merced and Davis have found that a secreted protein predominantly expressed in bone inhibits prostate cancer metastasis to bone.
Public Release: 16-Nov-2015 Pacific Northwest National Laboratory scientists win 5 R&D 100 awards
Technologies that impact cyber security, increase our ability to detect trace amounts of chemicals, convert sewage into fuel, view energy processes under real-world conditions and forecast future electric needs are among the newest R&D 100 award winners.
US Department of Energy, and others
Public Release: 2-Nov-2015
Nature Structural & Molecular Biology First complete pictures of cells' DNA-copying machinery
The first-ever images of the protein complex that unwinds, splits, and copies double-stranded DNA reveal something rather different from the standard textbook view. The electron microscope images, created by scientists at the US Department of Energy's Brookhaven National Laboratory with partners from Stony Brook University and Rockefeller University, offer new insight into how this molecular machinery functions.
National Institutes of Health
Public Release: 22-Oct-2015
Nature It takes a thief
The discovery by Berkeley Lab researchers of the structural basis by which bacteria are able to capture genetic information from viruses and other foreign invaders for use in their own immunological system holds promise for studying or correcting problems in human genomes.
National Science Foundation
Public Release: 21-Oct-2015 Berkeley Lab scientists to help build world's first total-body PET scanner
Scientists from Berkeley Lab have set out to help build the world's first total-body positron emission tomography scanner, a medical imaging device that could change the way cancers and other diseases are diagnosed and treated. The project is a consortium led by a UC Davis research team and includes scientists from Berkeley Lab and the University of Pennsylvania. It's supported by a recently announced five-year, $15.5 million Transformative Research Award from the National Institutes of Health.
National Institutes of Health
Public Release: 14-Oct-2015
SC15 Flowing toward red blood cell breakthroughs
A team led by Brown's George Karniadakis is using the Titan supercomputer at the Oak Ridge Leadership Computing Facility to simulate hundreds of millions of red blood cells in an attempt to develop better drug delivery methods and predictors to fight against tumor formation and sickle cell anemia.
US Department of Energy, National Institutes of Health
Public Release: 17-Aug-2015
Nature Scientists discover atomic-resolution details of brain signaling
Scientists have revealed never-before-seen details of how our brain sends rapid-fire messages between its cells. They mapped the 3-D atomic structure of a two-part protein complex that controls the release of signaling chemicals, called neurotransmitters, from brain cells. Understanding how cells release those signals in less than one-thousandth of a second could help launch a new wave of research on drugs for treating brain disorders.
Public Release: 13-Aug-2015 Sandia teams with industry to improve human-data interaction
Sandia National Laboratories and EyeTracking Inc. are researching computer information systems to make national security analysts better at getting meaningful information from large data sets coming in quickly in high-stress environments.
Public Release: 3-Aug-2015
Cell Host & Microbe Gut microbes affect circadian rhythms in mice, study says
A study including researchers from the US Department of Energy's Argonne National Laboratory and the University of Chicago found evidence that gut microbes affect circadian rhythms and metabolism in mice.
The Department of Energy's Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time.