Restriction Factor Smc6 (IMAGE) Université de Genève Caption The host restriction factor Smc6 (green) is located within the nucleus (blue) of uninfected human hepatocytes. In contrast, Smc6 is not present in HBV-infected hepatocytes (red). This confocal microscopy data provides direct evidence that Smc6 is degrades during HBV infection. Credit ©Gilead Sciences, Inc. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.