Normal Gene vs. Mutated Gene (IMAGE) University of Iowa Caption Here is a normal PTEN gene (top) as compared to a mutated PTEN gene (bottom), where the mutated gene will lose directional ability and its "false foot" (light blue) will force it to walk to different areas of the body and metastasize. Credit Illustrations courtesy of the Developmental Studies Hybridoma Bank, University of Iowa. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.