Protein Preps Cells to Survive Stress of Cancer Growth and Chemotherapy (IMAGE)

Salk Institute

Protein Preps Cells to Survive Stress of Cancer Growth and Chemotherapy

Caption

This image shows in brown color the activation of TGFβ signaling (left) and p53 levels (right) in a breast biopsy from a patient diagnosed with ductal carcinoma in situ and invasive carcinoma. TGFβ1 deactivates the main pathway directing the response to chemotherapeutic drugs and cellular stress, suggesting a potential new therapy to prevent early stages cancers progression and drug resistance.

Credit

Courtesy of the Salk Institute for Biological Studies

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