A New Ending to an Old 'Tail' (IMAGE)

Salk Institute

A New Ending to an Old 'Tail'

Caption

About 10 percent of tumor cells use a mechanism called ALT, short for alternative lengthening of telomeres, to keep their chromosomes ends intact. PML bodies that contain telomeric DNA and associated telomere-binding proteins (shown in orange) are highly characteristic of ALT tumor cells.

Credit

Courtesy of Dr. Liana Oganesian, Salk Institute for Biological Studies

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