Video Shows Formation of a Nuclear Bleb Prior to Nuclear Rupture (VIDEO)

Cornell University

Caption

CHMP4B-GFP transiently localizes to the site of NE rupture. HT1080 cell co- expressing CHMP4B-GFP and NLS-RFP migrating through a 2 × 5 μm2 constriction. Video shows formation of a nuclear bleb (black arrow) prior to nuclear rupture (red arrow) and subsequent rapid and transient recruitment of CHMP4B- GFP to the site of nuclear rupture (white arrowhead). Time interval: 2 min.

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Cornell University

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