The N14K Mutations Stabilizes the Open State of Cx26 Hemichannels (IMAGE)

Rockefeller University Press

The N14K Mutations Stabilizes the Open State of Cx26 Hemichannels

Caption

The X-ray crystallographic structure of two Cx26 subunits suggests that the N14K mutation in the protein's N-terminal domain (green) may stabilize the hemichannel's open state by interacting with a transmembrane domain (blue) of a neighboring subunit.

Credit

Sanchez <i>et al</i>., 2016

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