Cancer cells reprograCancer Cells Reprogrammed to iPmmed to iPS cells show aberrant differentiation. (IMAGE)

Center for iPS Cell Research and Application - Kyoto University

Cancer cells reprograCancer Cells Reprogrammed to iPmmed to iPS cells show aberrant differentiation.

Caption

Sarcoma cells that contain an oncogene, EWS-FLI1, and other mutations are reprogrammed to the pluripotent stem cell state (iPS cell). The iPS cell shows dysfunctional differentiation to osteoblast, a precursor for bone cell, suggesting a new mechanism for how cancer may form.

Credit

CiRA, Kyoto University

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