Schematic of Macrolactone 11 (IMAGE) Rice University Caption This is a schematic of macrolactone 11, currently under evaluation as a preclinical cancer drug candidate by the Rice University lab of K.C. Nicolaou. Based on the structure of the natural product and using a streamlined synthesis, the lab is developing analogues as drug candidates. Credit K.C. Nicolaou Group/Rice University Usage Restrictions For news reporting purposes only. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.