Severe Scoliosis (IMAGE) Washington University School of Medicine Caption Children with rare mutations in two genes are about four times more likely to develop severe scoliosis than their peers with normal versions of the genes, researchers have learned. Credit Matthew Dobbs Usage Restrictions Please credit Washington University School of Medicine in St. Louis License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.