Epigenomic Signature (IMAGE) Brigham and Women's Hospital Caption Researchers hypothesized that variation in the 'mutational landscape' might be influenced by chromatin structure, or the way that DNA is packaged, which varies widely from cell type to cell type. Credit Image courtesy of John Stamatoyannopoulos and Rae Senarighi Usage Restrictions Please credit John Stamatoyannopoulos and Rae Senarighi License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.