'Manhattan' Plot (IMAGE) University of Pennsylvania School of Medicine Caption This is a "Manhattan" plot demonstrating the locations across the chromosomes of the human genome (horizontal axis) where there was a statistically significant difference between genetic variants in the disease samples compared to normal individuals (vertical axis). The higher the dots, the stronger the genetic association. A very strong signal is seen in chromosome 7. Credit Van Deerlin et al, Nature Genetics, 2010 Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.