A New Lens on Colorectal Cancer (IMAGE) Arizona State University Caption New research shows the impact prostaglandin PGE2 has on the spread of CSCs to the liver. 'In cancer, the cells keep making PGE2 chronically, so it's like this wounding process that never heals. In doing so, it generates these cancer stem cells that promote cancer progression and metastatic spread', says lead author Ray DuBois, M.D., Ph.D. Credit Michael Northrop, Biodesign Institute, Arizona State University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.