Conquering Drug-Resistant Melanoma (IMAGE) The Wistar Institute Caption Three melanoma tumor spheroids, resistant to BRAF inhibitors, in a three-dimensional cell culture. Here, the difference between untreated living cells (green) and dead cells (blue) indicate success of a combination of MEK and PI3Ki inhibitors in killing resistant melanoma. Credit James Hayden/The Wistar Institute Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.