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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Sonic Hedgehog Control of Brain Development

Caption: Comparison of expression of a reporter gene under the regulatory control of a wild type and mutant Shh brain enhancer - SBE2 (blue). Note that the reporter gene is expressed more fully from the wild type (WT) versus the mutant (Mut) Shh enhancer in the hypothalamus of a 10-day-old mouse embryo.

Credit: Douglas J. Epstein, University of Pennsylvania School of Medicine

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Related news release: Penn researchers find key to Sonic hedgehog control of brain development


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