Contact: Greg Lester
gregory.lester@fccc.edu
215-316-8977
Fox Chase Cancer Center

Mutated BubR1 Makes a Mess of Chromosome Segregation

Caption: Left: Normal metaphase, kinetochores (red dots) attach to chromosomes (not visible), which are then pulled apart by microtubules (green lines). Right: A mutation in BubR1 cause kinetochores to create aberrant attachments to chromosomes, leading to improper segregation.

Credit: Fox Chase Cancer Center

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