Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Donor-Recipient Genetics and Early Kidney Transplant Complications

Caption: The three-dimensional structure mapping of the amino acid sequence in the antigen binding domain of the HLA-A molecule. The amino acid sequence was mapped onto its molecular surface. Amino acid variability at position 62 (an important T cell receptor contact site) and 163 (a peptide and a T cell receptor contact site) were found to be associated with increased risk of delayed allograft function.

Credit: Malek Kamoun MD, Ph.D., University of Pennsylvania

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