Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Molecular Origin of Blood Stem Cells

Caption: During development, a small number of endothelial cells express Runx1 (blue cells), signaling the production of grapelike clusters of hematopoietic (or blood) stem cells along the interior walls of several major blood vessels in the mouse embryo. This cluster of endothelial cells is in the lumen of the vitelline artery.

Credit: Nancy Speck, PhD, University of Pennsylvania School of Medicine.

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Related news release: Penn Researchers Unlock Molecular Origin of Blood Stem Cells