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Contact: Ed Hayward
Boston College

Cardiolipin Abnormalities

Caption: These three-dimensional illustrations show the relationship of cardiolipin abnormalities to electron transport chain activities in the cells of mouse brain tumors studied by researchers from Boston College and Washington University School of Medicine. The graphs show the position of the tumors in relation to their host strain in three enzyme complexes. The team reported in the Journal of Lipid Research new findings that support the Warburg Theory of Cancer. The new research contends that cancer could arise from genomic mutations, environmental insults, or from epigenetic (gene-environmental) abnormalities, any of which could damage cardiolipin and ultimately produce irreversible injury to cellular respiration.

Credit: The Journal of Lipid Research

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Related news release: Nearly a century later, new findings support Warburg theory of cancer

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