The Breakdown of Barriers in Old Cells May Hold Clues to Aging Process

Contact: Gina Kirchweger
Kirchweger@salk.edu
858-453-410-01340
Salk Institute

The Breakdown of Barriers in Old Cells May Hold Clues to Aging Process

Caption: In aging cells one of the proteins composing nuclear pores becomes damaged and molecules that should be restricted to the cytoplasm invade the nucleus (outline shown in red). In particular, a protein called tubulin (shown in green), which is strictly a cytoplasmic protein, shows up as long filaments that co-opt a large part of the nucleus.

Credit: Courtesy of Dr. Maximiliano D'Angelo, Salk Institute for Biological Studies.

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