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Foxc2 and NFATAc1 at Work

Caption: Normal valve-containing lymph vessels (left) fail to form in mice that lack Foxc2 and NFATc1 (right). The study by Norrmén et al. suggests that these two transcription factors direct the building of mature lymph-collecting vessels by coming together to regulate target gene loci.

Credit: Norrmén, C., et al. 2009. J. Cell Biol. doi:10.1083/jcb.200901104.

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