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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Caption: Screening many classes of compounds for activity of small molecule candidate drugs in p53 mutant cancer cells. Using light-emitting reporter genes and imaging technology the investigators were able to detect which compounds restored p53-responsivity and killed the mutant cancer cells.
Credit: Wafik El-Deiry, MD, PhD, University of Pennsylvania School of Medicine; Proceedings of the National Academy of Sciences
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Related news release: Imaging technology points to small molecules that can fight treatment-resistant tumors
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