Multicellular Architecture Regulates Cellular Function (2 of 2) (image) University of Pennsylvania Share Print E-Mail Caption Immunofluorescence sections of cells embedded within a micropatterned collagen gel. Cells generate forces within a tissue that can feedback to regulate the accumulation of cytoskeletal proteins such as actin (green) and structural matrix proteins such as fibronectin or tenascin C (red) in a spatially dependent manner. Cell nuclei are labeled in blue. Credit Image courtesy of Wesley R Legant Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.