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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

New Smallpox Protein Structure Could Aid in Drug Design

Caption: Three-dimensional rotation view of the smallpox virus topoisomerase enzyme-DNA complex (DNA, yellow; topoisomerase, blue; covalent bond between the topoisomerase and the DNA, pink sphere)

Credit: Kay Perry, Ph.D.; Frederic D. Bushman, Ph.D.; Gregory D. Van Duyne, Ph.D., University of Pennsylvania School of Medicine; Molecular Cell

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Related news release: Penn researchers determine structure of smallpox virus protein bound to DNA


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