Contact: Lena Raditsch
European Molecular Biology Laboratory
Caption: In the center, a structural model determined by X-ray crystallography shows how the two tags (attached to a short section of the histone protein -- all in cyan) fit neatly into the Brdt pocket (purple). In the background image, hypercompaction by Brdt causes relatively diffuse chromatin (stained blue inside the nuclei of two cells on the top left) to compact and clump together (two on the bottom right).
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