PIKfyve Directs Calcium Channel Degradation (image) Rockefeller University Press Caption With glutamate stimulation (right), CaV1.2 channels (red) are internalized and degraded by cortical neurons under PIKfyve's direction. Credit Tsuruta, F., et al. 2009. J. Cell Biol. doi:10.1083/jcb.200903028. Usage Restrictions Reporters may freely use these materials in news coverage, with the appropriate credit information. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.