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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-459-0544
University of Pennsylvania School of Medicine

Reversal of Blindness in Children

Caption: Researchers from the University of Pennsylvania School of Medicine and the Center for Cellular and Molecular Therapeutics at the Children's Hospital of Philadelphia have used gene therapy to safely improve vision in five children and seven adults with a rare form of congenital blindness. Albert M. Maguire, M.D., associate professor of Ophthalmology at Penn and a physician at the Children's Hospital of Philadelphia; Katherine High, M.D., director of the Center for Cellular and Molecular Therapeutics at the Children's Hospital of Philadelphia; Investigator, Howard Hughes Medical Institute and Jean Bennett, M.D., Ph.D., professor of ophthalmology, at Penn are co-authors of the reversal of blindness in children study published in the Lancet. The gene therapy vector (shown) used in the study was manufactured at the Center for Cellular and Molecular Therapeutics at the Children's Hospital of Philadelphia.

Credit: Children's Hospital of Philadelphia

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Related news release: 1 shot of gene therapy and children with congenital blindness can now see


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