Contact: Sonia Furtado
sonia.furtado@embl.de
European Molecular Biology Laboratory

Somatic Reprogramming of Ovaries to Testes

Caption: These microscopy images show the cellular reprogramming uncovered by EMBL scientists. On the left is an ovary of a normal adult female mouse, with a close-up (top left) showing the typical female granulosa cells. When the Foxl2 gene was silenced in these cells (right, top right: close-up), they took on the characteristics of Sertoli cells, the cells normally found in testes of male mice.

Credit: Treier/EMBL

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