Contact: Kat Snodgrass
Society for Neuroscience
Caption: Proposed model for the role of the blood protein fibrinogen that triggers scar formation in the brain and spinal cord. Fibrinogen carries an inactive substance called TGF-B, which circulates in the bloodstream of an uninjured nervous system (left panel). When there’s an injury and blood vessels leak, TGF-B interacts with local brain cells and sends signals that result in scar formation (right panel).
Credit: Courtesy, with permission: Schachtrup et al. The Journal of Neuroscience 2010.
Usage Restrictions: For reporters, free use with appropriate credit line. All others, please contact The Journal of Neuroscience.
Related news release: Blood protein triggers scars in the brain after injury