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Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley
Caption: The cytoskeleton of mesenchymal stem cells shows the orientation of stem cells on micropatterned membranes. On unpatterned membranes, stem cells naturally orient randomly, but realign perpendicularly to the axis of stretch when repeatedly stretched. However, on membranes with micropatterned grooves, stem cells align with the grooves and remain aligned even when stretched. Note: direction of stretch is left to right, and the orientation of microgrooves is left to right.
Credit: Image courtesy of Kyle Kurpinski, UC Berkeley
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