Accumulation of Defective Mitochondria (image) Rockefeller University Press Caption Parkin (green) promotes the turnover of damaged mitochondria (red, left), but defective organelles accumulate near the nucleus if Parkin lacks its ubiquitin ligase activity (right). Credit Lee, J.-Y., et al. 2010. J. Cell Biol. doi:10.1083/jcb.201001039. Usage Restrictions Reporters may freely use these materials in news coverage, with the appropriate credit information. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.