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Alpha-synuclein Reduces Autophagosomes

Caption: An abundance of alpha-synuclein (right) reduces the number of autophagosomes (bright puncta, left), the double-membraned vesicles that remove trash from the cell. Blocking autophagosome formation in this way may contribute to neurodegeneration in Parkinsonís patients.

Credit: Winslow, A.R., et al. 2010. J. Cell Biol. doi:10.1083/jcb.201003122.

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