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Contact: Emily Carlson
carlsone@nigms.nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences

Modeling How HIV Latches on to Immune Cell Receptors

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Caption: This model shows how HIV, in gray, might latch on to immune cell receptor molecules, allowing the virus to enter and infect the cell. The viral protein, gp120, shown in light blue, binds to receptors CD4 and CXCR4, shown in tan and dark blue. Models like this one allow scientists to test their ideas about how HIV gains access to cells -- and help pinpoint important targets for developing drugs to impede HIV.

Credit: Animation courtesy of Gye Won Han of the Scripps Research Institute. Video produced by the National Institute of General Medical Sciences, part of the National Institutes of Health.

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