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Caption: These are cancer cells from a squamous cell lung cancer patient with clusters of copies of the FGFR1 gene (red signals). This high copy number of FGFR1 indicates that FGFR1 can be targeted therapeutically in this lung cancer patient. This image relates to an article that appeared in the Dec. 15, 2010, issue of Science Translational Medicine, published by AAAS. The study, by Dr. J. Weiss at Max Planck Institute for Neurological Research in Cologne, Germany, and colleagues, was titled, "Frequent and Focal FGFR1 Amplification Associates With Therapeutically Tractable FGFR1 Dependency in Squamous cell Lung Cancer."
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