Global Distribution of the Sickle Cell Gene and Malaria Incidence (image) Instituto Gulbenkian de Ciencia Share Print E-Mail Caption These maps show the worldwide distribution of the mutation responsible for the sickle cell trait (a and b) and of malaria incidence (c). Regions where the sickle cell mutation occurs overlap neatly with areas in Africa where malaria is endemic. Credit Source: Piel et al. (2010). Nature Communications Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.