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Rockefeller University Press

Aurura A in PKD Cysts

Caption: Red staining indicates the presence of activated Aurora A kinase in the epithelial cells lining cysts in the kidneys of patients with polycystic kidney disease (PKD). A new study in The Journal of Cell Biology suggests that Aurora A may contribute to PKD, a common genetic disease, by inactivating a key calcium channel in kidney cells.

Credit: Plotnikova, O.V., and E.A. Golemis. 2011. J. Cell Biol. doi:10.1083/jcb.201012061.

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Related news release: Aurora A may contribute to kidney disease


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