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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Caption: Daily variation in blood pressure in normal mice versus mice in which clock genes have been disrupted. In mice with normal clock protein (BMAL) function, blood pressure rises during the morning hours (left). In BMAL knockout mice, the daily variation in blood pressure vanishes (right).
Credit: Annie M. Curtis, Ph.D., and Garret A. FitzGerald, M.D., University of Pennsylvania School of Medicine; Proceedings of the National Academy of Sciences
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Related news release: First molecular evidence of body's internal clock in controlling blood pressure
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