This image shows ATRX protein staining in brown. ATRX protein is clearly is missing from the nuclei of the cancer cells (here stained blue) which are here surrounding a normal blood vessel whose cells display ATRX protein positivity in their nuclei (brown). This image relates to an article that appeared in the June 30, 2011, issue of Science Express, published by AAAS. The study, by C.M. Heaphy of Johns Hopkins Medical Institutions in Baltimore, Md., and colleagues was titled, "Altered Telomeres in Tumors with ATRX and DAXX Mutations."