Similar to the previous image, except these cells tried to divide several times and all unsuccessfully. This led to the shape of its nucleus. This image relates to a paper that appeared in the Aug. 10, 2011, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. A.V. Gasparian of Cleveland BioLabs Inc. in Buffalo, N.Y., and colleagues, was titled, "Curaxins: Anticancer Compounds that Simultaneously Suppress NF-kB and Activate p53 by Targeting FACT."