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Caption: This image shows the death of curaxin treated tumor cell. Immunofluorescent image of non-fixed cells. Red -– red fluorescent protein (RFP) tagged histone H2B. Green -– green fluorescent protein (GFP) tagged SSRP1 subunit of FACT. This image relates to a paper that appeared in the Aug. 10, 2011, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. A.V. Gasparian of Cleveland BioLabs Inc. in Buffalo, N.Y., and colleagues, was titled, "Curaxins: Anticancer Compounds that Simultaneously Suppress NF-kB and Activate p53 by Targeting FACT."
Credit: Image © Science/AAAS
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