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Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America

Hologram vs. Conventional Microscope

Caption: These pictures compare a piece of skin tissue imaged with the holographic microscope to the same piece of tissue imaged with a conventional microscope. The top two images (a-b) show the raw, unprocessed hologram -- the light interference pattern -- that is collected by the microscope’s sensor in reflection mode; the second image (b) is a zoomed-in version of the first (a). A computer-reconstructed image of this skin tissue is at the bottom left (c). The bottom right (d) shows a picture of the same specimen taken with a conventional, objective-lens microscope, for comparison.

Credit: Ozcan BioPhotonics Group at UCLA/Biomedical Optics Express.

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Related news release: Microscope on the go: Cheap, portable, dual-mode microscope uses holograms, not lenses


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