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Contact: Rachel Champeau
University of California - Los Angeles Health Sciences

Reversal of Diseased Pulmonary and Heart Structure with Estrogen Treatment

Caption: Image shows a normal control lung blood vessel and heart (CTRL) compared with these structures affected by pulmonary hypertension (PH), at the advanced disease stage of right ventricle failure (RVF) and disease reversal with estrogen treatment (E2) and continued benefit even after estrogen treatment withdrawal (E2-W). Note the completely blocked blood vessel and enlarged right ventricle in advanced disease (RVF) and how the right ventricle (RV) shrinks and vessel clears during and after estrogen treatment (E2) and (E2-W).

Credit: American Journal of Respiratory and Critical Care Medicine/UCLA

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Related news release: Estrogen treatment may help reverse severe pulmonary hypertension

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